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T12642(R)-Simurosertib(R)-Simurosertib,(R)-TAK-931,
(R)-Simurosertib is the (R)-enantiomer of Simurosertib. Simurosertib is an orally active, selective and ATP-competitive cell division inhibitor of cycle 7 (CDC7) kinase(IC50 of <0.3 nM).
价 格:¥电议型 号:T12642产 地:美洲
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T15632JW 642JW 642
JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL) (IC50: 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively).
价 格:¥电议型 号:T15632产 地:美洲
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T1642LenalidomideLenalidomide,CC-5013,
Lenalidomide is a potent inhibitor of TNF-α that, at 10 μM, alters gene expression and cell viability in a range of cancer cell lines.
价 格:¥电议型 号:T1642产 地:美洲
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T16420P-1075P-1075
P-1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species causing cardioprotection of rabbit hearts. P-1075 is an effective activator of sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-KIR6) (EC50: 45 nM fo
价 格:¥电议型 号:T16420产 地:美洲
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T16421p-MPPI hydrochloridep-MPPI hydrochloride
p-MPPI hydrochloride can cross the blood-brain barrier and has clear antidepressant and anxiolytic-like effects. p-MPPI hydrochloride is a selective 5-HT1A receptor antagonist. It has a high affinity for 5-HT1A receptors.
价 格:¥电议型 号:T16421产 地:美洲
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T16423p32 Inhibitor M36p32 Inhibitor M36,M36,
p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.
价 格:¥电议型 号:T16423产 地:美洲
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T16424p38 MAPK-IN-1p38 MAPK-IN-1
p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM).
价 格:¥电议型 号:T16424产 地:美洲
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T16425PA452PA452
PA452 is a retinoic X receptor (RXR) specific antagonist. PA452 suppresses the effect of Retinoic acid (RA) on Th1/Th2 development.
价 格:¥电议型 号:T16425产 地:美洲
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T16426AsivatrepAsivatrep,PAC-14028,
Asivatrep is an effective and selective transient receptor potential vanilloid type I antagonist.
价 格:¥电议型 号:T16426产 地:美洲
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T16427PadsevonilPadsevonil,UCB-0942,
Padsevonil is an effective antiepileptic compound.
价 格:¥电议型 号:T16427产 地:美洲
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T16428PafuramidinePafuramidine,DB289,
Pafuramidine is an orally bioavailable prodrug of furamidine. It has activity against Pneumocystis pneumonia (IC50 value: 4.5 nM)
价 格:¥电议型 号:T16428产 地:美洲
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T16429GNE 2861GNE 2861
GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.
价 格:¥电议型 号:T16429产 地:美洲
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T2238CariporideCariporide,HOE-642,
Cariporide (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (PAC-1).
价 格:¥电议型 号:T2238产 地:美洲
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T2642PD173074PD173074
PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src.
价 格:¥电议型 号:T2642产 地:美洲
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T5134Vilanterol trifenatateVilanterol trifenatate,GW642444 (trifenatate),
Vilanterol trifenatate is a long-acting agonist of β2-adrenoceptor (β2-AR) with inherent 24-hour activity(β2-AR, β1-AR and β3-AR pEC50s of 10.37, 6.98 and 7.36, respectively)
价 格:¥电议型 号:T5134产 地:美洲
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T5642BC2059BC2059
BC2059 is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.
价 格:¥电议型 号:T5642产 地:美洲
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T6108Ki16425Ki16425,Debio 0719,
Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.
价 格:¥电议型 号:T6108产 地:美洲
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T6420BMS-707035BMS-707035,BMS707035,BMS 707035
BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.
价 格:¥电议型 号:T6420产 地:美洲
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T6421BRD73954BRD73954
BRD73954, an effective and specific HDAC inhibitor, which is with IC50 of 36 nM and 120 nM for HDAC6 and HDAC8, respectively.
价 格:¥电议型 号:T6421产 地:美洲