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T3634Osimertinib mesylate甲磺酸奥希替尼;奥希替尼甲磺酸盐;Mereletinib mesylate;AZD-9291 mesylate
Osimertinib (AZD-9291) is an irreversible and mutant selective EGFR inhibitor (IC50s: 12/1 nM for EGFR(L858R) and EGFR(L858R/T790M)).
价 格:¥电议型 号:T3634产 地:中国大陆
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T3536AZD1283
AZD1283 is an effective P2Y12 receptor antagonist (EC50: 3.0 ug/kg/min, binding IC50: 11 nM). AZD1283 dose-dependently induced increases in blood flow and inhibition of ADP-induced platelet aggregation with antithrombotic ED50 values of 3.0 and 10 μg/kg/m
价 格:¥电议型 号:T3536产 地:中国大陆
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T3504AZD5153 6-Hydroxy-2-naphthoic acidAZD5153;AZD-5153 HNT salt;AZD5153结晶体(API形式)
AZD5153 (6- Hydroxy- 2- naphthoic Acid) is a potent triazolopyridazine-based Bromodomain (BRD4) and Extraterminal (BET) inhibitor used in cancer treatments.
价 格:¥电议型 号:T3504产 地:中国大陆
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T3338CeralasertibAZD6738
AZD6738 is an orally active, and selective ATR kinase inhibitor with IC50 of 1 nM.
价 格:¥电议型 号:T3338产 地:中国大陆
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T3210AZD3965AZD 3965;AZD-3965
AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1).
价 格:¥电议型 号:T3210产 地:中国大陆
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T3107AlvelestatAZD9668;Avelestat
Alvelestat is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.
价 格:¥电议型 号:T3107产 地:中国大陆
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T3069AZD-1480AZD1480
AZD1480 is a novel ATP-competitive JAK2 inhibitor (IC50: 0.26 nM), selectivity act against Tyk2 and JAK3, and to a smaller extent against JAK1. AZD1480 has been used in trials studying the treatment of Solid Malignancies, Post-Polycythaemia Vera, Primary
价 格:¥电议型 号:T3069产 地:中国大陆
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T30258AZD-4818CCR1 antagonist;AZD4818;AZD 4818
AZD-4818 is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.
价 格:¥电议型 号:T30258产 地:中国大陆
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T3015OlaparibAZD2281;KU0059436;奥拉帕尼
Olaparib is a small molecule inhibitor of PARP1/PARP2 (IC50: 5/1 nM) but is less effective against the PARP tankyrase-1 (IC50: 1.5 μM).
价 格:¥电议型 号:T3015产 地:中国大陆
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T26712AZD-1656AZD 1656;AZD1656
AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2 diabetes.
价 格:¥电议型 号:T26712产 地:中国大陆
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T2602Barasertib-HQPABarasertib;AZD1152-HQPA;1H-Pyrazole-3-acetamide;AZD2811;AZD1152-HQPA|AZD2811
Barasertib (AZD1152-HQPA) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.
价 格:¥电议型 号:T2602产 地:中国大陆
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T2506AZD-5438AZD5438
AZD5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).
价 格:¥电议型 号:T2506产 地:中国大陆
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T2500Cediranib西地尼布;AZD2171;NSC-732208
Cediranib (AZD2171) is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro, also inhibits Flt1/4 (IC50: 5 nM/≤3 nM), similar activity against PDGFRβ and c-Kit, selective more for VEGFR than PDGFR-α (36-f
价 格:¥电议型 号:T2500产 地:中国大陆
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T2490OsimertinibMereletinib;AZD-9291;奥希替尼
Osimertinib is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of advanced non-small cell lung cancer (NSCLC).
价 格:¥电议型 号:T2490产 地:中国大陆
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T2300AZD1208
AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.
价 格:¥电议型 号:T2300产 地:中国大陆
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T21544AZD-5597(S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(m
AZD-5597 is a potent imidazole pyrimidine amide CDK inhibitor.
价 格:¥电议型 号:T21544产 地:中国大陆
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T21474NavuridineCS87;CS-87;AzUrd;CS 87;AZdU;AZddU
Navuridine is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.
价 格:¥电议型 号:T21474产 地:中国大陆
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T2077AdavosertibMK-1775;AZD1775;Adavosertib (MK-1775)
MK-1775 is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.
价 格:¥电议型 号:T2077产 地:中国大陆