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  • T1967AZD-3463ALK/IGF1R inhibitor;AZD3463

    AZD3463, an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.

    价 格:¥电议型 号:T1967产 地:中国大陆

  • T1961VistusertibAZD2014

    AZD2014 is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.

    价 格:¥电议型 号:T1961产 地:中国大陆

  • T1957AZD2858

    AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway.

    价 格:¥电议型 号:T1957产 地:中国大陆

  • T1948AZD4547

    AZD4547, a new-type specific FGFR inhibitor, targets for FGFR1/2/3 (IC50: 0.2/2.5/1.8 nM in cell-free assays).

    价 格:¥电议型 号:T1948产 地:中国大陆

  • T1920CapivasertibAZD5363

    Capivasertib (AZD5363) is a new-type orally available inhibitor of the serine/threonine protein kinase AKT (IC50s: 3/7/7 nM for Akt1/2/3).

    价 格:¥电议型 号:T1920产 地:中国大陆

  • T1859AZD-8055AZD8055

    AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.

    价 格:¥电议型 号:T1859产 地:中国大陆

  • T1836AZD2932

    AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.

    价 格:¥电议型 号:T1836产 地:中国大陆

  • T1741AZD1080

    AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.

    价 格:¥电议型 号:T1741产 地:中国大陆

  • T16486Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZDPF-05231023

    PF-05231023 is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist. It is also suitable for development as a potential treatment for T2DM.

    价 格:¥电议型 号:T16486产 地:中国大陆

  • T16162Mutated EGFR-IN-1Osimertinib analog;AZD9291中间体1

    Mutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant, and T790M resistance mutant.

    价 格:¥电议型 号:T16162产 地:中国大陆

  • T14388AZD 4017

    AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).

    价 格:¥电议型 号:T14388产 地:中国大陆

  • T14385AZD9056 hydrochloride

    AZD9056 hydrochloride is a P2X7 inhibitor,Which plays a significant role in pain-causing diseases and inflammation.

    价 格:¥电议型 号:T14385产 地:中国大陆

  • T14381AZD7624AZD-7624

    AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.

    价 格:¥电议型 号:T14381产 地:中国大陆

  • T14380AZD7507

    AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.

    价 格:¥电议型 号:T14380产 地:中国大陆

  • T14379AZD5904

    AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO, IC50: 140 nM) which has similar potency in mouse and rat.

    价 格:¥电议型 号:T14379产 地:中国大陆

  • T14378LAZD5582 acetate (1258392-53-8 free base)

    AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. AZD5582 induces apoptosis.

    价 格:¥电议型 号:T14378L产 地:中国大陆

  • T14377AZD5423

    AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma.

    价 格:¥电议型 号:T14377产 地:中国大陆

  • T14376AZD4320

    AZD4320 is an inhibitor of BH3-mimicking dual BCL2/BCLxL. For KPUM-MS3, KPUM-UH1, and STR-428 cells, the IC50s values are 26 nM, 17 nM, and 170 nM , respectively.

    价 格:¥电议型 号:T14376产 地:中国大陆

  • T14369AZD-0284

    AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders[1].

    价 格:¥电议型 号:T14369产 地:中国大陆

  • T10435Linaprazan利那拉生;AZD0865

    Linaprazan inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.

    价 格:¥电议型 号:T10435产 地:中国大陆

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