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T62430HIV-1 inhibitor-24;化合物 HIV-1 inhibitor-24HIV-1 inhibitor-24
HIV-1 inhibitor-24 (compound S-12a) is a potent inhibitor of HIV-1 reverse transcription (HIV-1 RT) (IC50: 9.5 nM). HIV-1 inhibitor-24 exhibits a high antiviral effect on wild-type HIV-1 with an EC50 value of 1.6 nM and low cytotoxicity (CC50 on MT-4 cells). HIV-1 inhibitor-24 was well tolerated in mice at a dose of 2 g/kg and had a significant cardiovascular safety profile.
价 格:¥电议型 号:T62430产 地:中国大陆
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T6243U-73122;化合物U73122U73122;U73122
U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.
价 格:¥电议型 号:T6243产 地:中国大陆
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T62429TRK-IN-14;化合物 TRK-IN-14TRK-IN-14
TRK-IN-14 is a potent inhibitor of TRK. TRK-IN-13 has shown potential for TRK-related diseases.
价 格:¥电议型 号:T62429产 地:中国大陆
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T62428TRK-IN-13;化合物 TRK-IN-13TRK-IN-13
TRK-IN-13 is a potent inhibitor of TRK. TRK-IN-13 has shown potential for the study of TRK-related diseases.
价 格:¥电议型 号:T62428产 地:中国大陆
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T62427Anticancer agent 32;化合物 Anticancer agent 32Anticancer agent 32
Anticancer agent 32 (compound 2g) is an anticancer agent that exhibits anticancer effects by affecting the cell cycle and inducing apoptosis. anticancer agent 32 can be used in cancer research.
价 格:¥电议型 号:T62427产 地:中国大陆
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T62426GABAA receptor agent 2 TFA;化合物 GABAA receptor agent 2 TFAGABAA receptor agent 2 TFA
GABAA receptor agent 2 TFA is a potent, high-affinity GABAA receptor antagonist with an IC50 of 24 nM (human α1β2γ2GABAA-expressing tsA201 cells) and a Ki of 28 nM (rat GABAA receptor). GABAA receptor agent 2 TFA has no effect on four human GABA transport proteins (hGAT-1, hBGT-1, hGAT-2 and hGAT-3).
价 格:¥电议型 号:T62426产 地:中国大陆
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T62425sEH inhibitor-3;化合物 sEH inhibitor-3sEH inhibitor-3
sEH inhibitor-3 (compound 35) is a potent, orally active inhibitor of soluble epoxide hydrolase (sEH) that acts on human sEH (Ki: 0.75 nM).
价 格:¥电议型 号:T62425产 地:中国大陆
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T62424L-Moses dihydrochloride;化合物 L-Moses dihydrochlorideL-Moses dihydrochloride
L-Moses (L-45) dihydrochloride is the first, potent, selective p300/CBP-associated factor (PCAF) bromodomain (Brd) inhibitor (Kd: 126 nM).
价 格:¥电议型 号:T62424产 地:中国大陆
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T62423GCPII-IN-1 TFA;化合物 GCPII-IN-1 TFAGCPII-IN-1 TFA
GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII; PSMA) inhibitor scaffold (Ki: 44.3 nM).
价 格:¥电议型 号:T62423产 地:中国大陆
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T62422Nav1.8-IN-2;化合物 Nav1.8-IN-2Nav1.8-IN-2
Nav1.8-IN-2 (compound 35A) is a potent inhibitor of Nav1.8 (IC50: 0.4 nM). Nav1.8-IN-2 can be used in studies of pain disorders, cough, acute and chronic pruritus.
价 格:¥电议型 号:T62422产 地:中国大陆
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T62421Buclizine;化合物 BuclizineBuclizine
Buclizine is an orally active antihistamine, antiallergic compound. buclizine is also a strong teratogen in rats and exhibits antitumour effects.
价 格:¥电议型 号:T62421产 地:中国大陆
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T62420P2Y2R/GPR17 antagonist 1;P2Y2R/GPR17拮抗剂1P2Y2R/GPR17 antagonist 1
P2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual P2Y2R (IC50: 3.17 μM) and GPR17 (IC50: 1.67 μM) antagonist.
价 格:¥电议型 号:T62420产 地:中国大陆
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T6242Rupatadine Fumarate;富马酸卢帕他定Rinialer|||Rupafin|||Alergoliber;富马酸卢帕他定|||Rinialer|||Rupafin|||Alergolib
Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM.
价 格:¥电议型 号:T6242产 地:中国大陆
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T62419Antifungal agent 13;化合物 Antifungal agent 13Antifungal agent 13
Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.
价 格:¥电议型 号:T62419产 地:中国大陆
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T62418hACC2-IN-1;化合物 hACC2-IN-1hACC2-IN-1
hACC2-IN-1 is a potent inhibitor of acetyl coenzyme A carboxylase 2 (ACC2) with an IC50 value of 2.5 μM for hACC2. hACC2-IN-1 has potential for obesity studies.
价 格:¥电议型 号:T62418产 地:中国大陆
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T62417MELK-8a;化合物 MELK-8aMELK-8a
MELK-8a (NVS-MELK8a) is a potent and selective inhibitor of maternal embryonic leucine elongation kinase (MELK) (IC50: 2 nM). 0.42 μM). Among them, MELK plays an important role in regulating mitosis in cancer cells.
价 格:¥电议型 号:T62417产 地:中国大陆
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T62416DX2-201;化合物 DX2-201DX2-201
DX2-201 is a potent and selective inhibitor of oxidative phosphorylation (OXPHOS) complex I (IC50: 312 nM) and exhibits anticancer activity.
价 格:¥电议型 号:T62416产 地:中国大陆
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T62415CBP/p300-IN-17;化合物 CBP/p300-IN-17CBP/p300-IN-17
CBP/p300-IN-17 (compound 7) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.18 μM) and LK2 H3K27 (IC50: 0.69 μM).
价 格:¥电议型 号:T62415产 地:中国大陆
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T62414Dyrk1A-IN-1;化合物 Dyrk1A-IN-1Dyrk1A-IN-1
Dyrk1A-IN-1 is a triple inhibitor of Dyrk1A kinase activity, aggregation of tau and α-syn oligomers, with an IC50 value of 119 nM for Dyrk1A kinase.
价 格:¥电议型 号:T62414产 地:中国大陆
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T62413SARS-CoV-2 nsp13-IN-1;化合物 SARS-CoV-2 nsp13-IN-1SARS-CoV-2 nsp13-IN-1
SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent inhibitor of nsp13 (non-structural protein 13). SARS-CoV-2 nsp13-IN-1 inhibits only nsp13 ssDNA+ATPase (IC50: 6 μM), but not ssDNA-ATPase. CoV-2 nsp13-IN-1 was able to be used to study COVID-19.
价 格:¥电议型 号:T62413产 地:中国大陆