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T62412FLT3-IN-12；化合物 FLT3-IN-12FLT3-IN-12
FLT3-IN-12 is a selective, potent, orally active FLT3 kinase inhibitor that acts on FLT3-WT (IC50: 1.48 nM) and FLT3-D835Y (IC50: 2.87 nM). FLT3-IN-12 is more selective than c-KIT (>1000-fold). FLT3-IN-12 showed significant anti-AML effects, with an IC50 value of 0.75 nM for MV4-11 cells.
价 格：￥电议型 号：T62412产 地：中国大陆
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T62411CB1/2 agonist 4；化合物 CB1/2 agonist 4CB1/2 agonist 4
CB1/2 agonist 4 (compound 24) is a CB1 full agonist (EC50: 15.09 nM) and a CB2 partial agonist (EC50: 1.16 nM). CB1/2 agonist 4 has significant anti-harm-sensing activity and also activates cannabinoid and TRPV1 receptors (IC50: 0.8 μM, EC50: 0.12 μM). , EC50: 0.12 μM).
价 格：￥电议型 号：T62411产 地：中国大陆
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T62410Hydroxyethylamine；化合物 HydroxyethylamineHydroxyethylamine
Hydroxyethylamine (Compd VII) is a SARS-CoV-2 3CLpro inhibitor with an IC50 of ~10 μM in a transmission assay. hydroxyethylamine exhibits significant antiviral effects.
价 格：￥电议型 号：T62410产 地：中国大陆
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T6241Quetiapine hemifumarate富马酸喹硫平Quetiapine Fumarate|||ICI-204636|||富马酸喹硫平
Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression.
价 格：￥电议型 号：T6241产 地：中国大陆
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T62409PI3K-IN-23；化合物 PI3K-IN-23PI3K-IN-23
PI3K-IN-23 is a (E)-9-oxooctadec-10-en-12-ynoic acid analogue that promotes glucose uptake (EC50: 7.00 μM).
价 格：￥电议型 号：T62409产 地：中国大陆
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T62408PI3Kδ-IN-11；化合物 PI3Kδ-IN-11PI3Kδ-IN-11
PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity. PI3Kδ-IN-11 can be used in B- or T-cell-associated malignancy studies.
价 格：￥电议型 号：T62408产 地：中国大陆
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T62407PDHK-IN-4；化合物 PDHK-IN-4PDHK-IN-4
PDHK-IN-4 (Compound 30) is a potent inhibitor of PDHK, acting on PDHK2 (IC50: 0.0051 μM) and PDHK4 (IC50: 0.0122 μM). PDHK-IN-4 has the potential to be investigated in cancer diseases.
价 格：￥电议型 号：T62407产 地：中国大陆
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T62406Nur77 modulator 2；化合物 Nur77 modulator 2Nur77 modulator 2
Nur77 modulator 2 is a Nur77 regulator with a Kd value of 0.35 μM. Nur77 modulator 2 is also a potent, orally active inhibitor of inflammation. nur77 modulator 2 regulates Nur77 co-localization in mitochondria.
价 格：￥电议型 号：T62406产 地：中国大陆
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T62405KDM1/CDK1-IN-1；化合物 KDM1/CDK1-IN-1KDM1/CDK1-IN-1
KDM1/CDK1-IN-1 (compound 4) is a potent inhibitor of KDM1 (IC50: 0.096 μM) and CDK1 (IC50: 0.078 μM). kDM1/CDK1-IN-1 blocks the cell cycle of HOP-92 cells in G2/M phase and induces apoptosis. KDM1/CDK1-IN-1 is highly cytotoxic to CCRF-CEM cells (IC50: 16.34 μM), HOP-92 cells (IC50: 3.45 μM) and Hep-G2 cells (IC50: 7.79 μM).
价 格：￥电议型 号：T62405产 地：中国大陆
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T62404SHMT-IN-2；化合物SHMT-IN-2SHMT-IN-2
SHMT-IN-2 (compound 2) is a specific human SHMT1/2 small molecule inhibitor that acts on SHMT1 (IC50: 13 nM) and SHMT2 (IC50: 66 nM). SHMT-IN-2 inhibits the growth of many human cancer cells and is sensitive to B-cell lymphoma.
价 格：￥电议型 号：T62404产 地：中国大陆
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T62403DM-01；化合物 DM-01DM-01
DM-01 is a potent and selective inhibitor of EZH2. DM-01 can be used to study diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL) and SNF5/INI-1/SMARCB1 gene-associated solid tumours.
价 格：￥电议型 号：T62403产 地：中国大陆
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T62402TTA-P2；化合物 TTA-P2TTA-P2
TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of the T-type calcium channel. TTA-P2 effectively penetrates the CNS and blocks natural T-type currents in deep cerebellar nucleus neurons, completely eliminating the window currents in wild-type and mutant Cav3.1 channels. research.
价 格：￥电议型 号：T62402产 地：中国大陆
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T62401Anti-infective agent 4；化合物 Anti-infective agent 4Anti-infective agent 4
Anti-infective agent 4 (compound 73) is an orally active Trypanosoma cruzi inhibitor (IC50: 0.016 μM). anti-infective agent 4 is effective in reducing parasite burden in vivo and can be used to study infections.
价 格：￥电议型 号：T62401产 地：中国大陆
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T62399Apoptosis inducer 10；化合物 Apoptosis inducer 10Apoptosis inducer 10
Apoptosis inducer 10 is a potent apoptosis inducer with anti-proliferative activity. apoptosis inducer 10 induces apoptosis in HeLa cancer cells using a mitochondria-dependent endogenous pathway.
价 格：￥电议型 号：T62399产 地：中国大陆
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T62398KH-3；化合物 KH-3KH-3
KH-3 is a potent inhibitor (IC50: 0.35 μM) of the RNA-binding protein Hu antigen R (HuR) and exhibits anti-proliferative effects. KH-3 interferes with HuR-FOXQ1 Mrna interactions, inhibits breast cancer cell invasion, and delays lung colony formation.
价 格：￥电议型 号：T62398产 地：中国大陆
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T62397Epitinib；化合物 EpitinibEpitinib
Epitinib is an orally active, selective, blood-brain barrier crossing epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI).
价 格：￥电议型 号：T62397产 地：中国大陆
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T62396LKB-5492 FA；KB-5492 甲酸盐KB-5492 FA（113594-64-2 Free base）；KB-5492 FA（113594-64-2 Free base）
KB-5492 FA is a selective sigma receptor inhibitor with antiulcerogenic effects.CAS ??128-52-56-8
价 格：￥电议型 号：T62396L产 地：中国大陆
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T62396KB-5492 free base；化合物 KB-5492 free baseKB-5492 free base
KB-5492 free base is an orally available and selective antiulcer agent that inhibits sigma receptors, inhibits [3H]1,3-di(2-tolyl)guanidine (DTG) binding to sigma receptors, and may be useful in the study of gastric lesions and gastric secretion.
价 格：￥电议型 号：T62396产 地：中国大陆
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T62395ALK5-IN-32；化合物 ALK5-IN-32ALK5-IN-32
ALK5-IN-32 is a selective inhibitor of ALK-5 (10 nM
价 格：￥电议型 号：T62395产 地：中国大陆
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T62394ALK5-IN-31；化合物 ALK5-IN-31ALK5-IN-31
ALK5-IN-31 is a selective inhibitor of ALK-5 (IC50≤10 nM) and also inhibits TGF-β-induced SMAD signalling.ALK5-IN-31 has the potential to inhibit tumour growth in vivo.ALK5-IN-31 can be used in the study of proliferative diseases (e.g. cancer, fibrotic diseases, systemic sclerosis).
价 格：￥电议型 号：T62394产 地：中国大陆
