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T62338IMPDH2-IN-2;化合物 IMPDH2-IN-2IMPDH2-IN-2
IMPDH2-IN-2 is a potent inhibitor of inosine 5´-monophosphate dehydrogenase (IMPDH) (Ki,app: 14 μM) and a potential anti-tuberculosis agent. IMPDH2-IN-2 has a moderate antibacterial effect with MIC values of 6.3 and 11 μM in minimal GAST/Fe and rich 7H9/ADC/Tween media, respectively. μM.
价 格:¥电议型 号:T62338产 地:中国大陆
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T62337CDK2-IN-11;化合物 CDK2-IN-11CDK2-IN-11
CDK2-IN-11 (compound 9d) is a potent inhibitor of CDK2 (IC50: 6.4 μM) and acts on hCA II (Ki: 23.4 nM), hCA IX (Ki: 56.3 nM) and hCA XII (Ki: 44.3 nM). CDK2-IN-11 can be used in anticancer studies.
价 格:¥电议型 号:T62337产 地:中国大陆
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T62336BChE-IN-3;化合物 BChE-IN-3BChE-IN-3
BChE-IN-3 is a selective, selective, time-dependent, pseudo-irreversible inhibitor of BChE butyrylcholinesterase (IC50: 56.9 nM).BChE-IN-3 exhibits borderline reversible (time-independent) inhibition of AChE acetylcholinesterase.
价 格:¥电议型 号:T62336产 地:中国大陆
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T62335MDH1-IN-2;MDH抑制剂2MDH1-IN-2
MDH1-IN-2 is a potent MDH1 inhibitor with potential anticancer activity for the study of diseases related to the immune system.
价 格:¥电议型 号:T62335产 地:中国大陆
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T62334VII-31;化合物 VII-31VII-31
VII-31 is a NEDDylation pathway activator that induces apoptosis and exhibits tumour inhibition in vitro and in vivo.
价 格:¥电议型 号:T62334产 地:中国大陆
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T62333Anti-Trypanosoma cruzi agent-1;化合物 Anti-Trypanosoma cruzi agent-1Anti-Trypanosoma cruzi agent-1
Anti-Trypanosoma cruzi agent-1 (Compd E5) has a potent anti-Toxoplasma effect.
价 格:¥电议型 号:T62333产 地:中国大陆
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T62332Tubulin inhibitor 13;化合物 Tubulin inhibitor 13Tubulin inhibitor 13
Tubulin Inhibitor 13 (E27) effectively inhibits tubulin polymerization with an IC50 of 16.1 μM. This compound also restricts cancer cell migration and invasion, promotes apoptosis, and exhibits notable anticancer activity [1].
价 格:¥电议型 号:T62332产 地:中国大陆
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T62331Autophagy-IN-1;化合物 Autophagy-IN-1Autophagy-IN-1
Autophagy-IN-1 is a potent inhibitor of autophagy/mitophagy, blocking autophagosomal-lysosomal fusion in cancer cells while selectively increasing autophagic flux. Autophagy-IN-1 significantly inhibits tumour growth in the HCT116 mouse xenograft tumour model with low toxicity.Autophagy-IN-1 can be used to study colorectal cancer.
价 格:¥电议型 号:T62331产 地:中国大陆
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T62330Antileishmanial agent-12;化合物 Antileishmanial agent-12Antileishmanial agent-12
Antileishmanial agent-12 (compound 5a) is a potent anti-leishmanial agent with antibacterial activity against Leishmania brazilensis (IC50: 14.9 μM), Leishmania infantum (IC50: 21.3 μM) and T. cruzi (IC50. 9.3 μM). 9.3 μM) had antiprotozoal effects.
价 格:¥电议型 号:T62330产 地:中国大陆
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T6233Entinostat;恩替诺特SNDX-275|||MS-275;恩替诺特|||SNDX-275|||MS-275
Entinostat (MS-275) (MS-275) is an inhibitor of HDACs that inhibits HDAC1 and HDAC3 (IC50s: 0.18/0.74 μM).
价 格:¥电议型 号:T6233产 地:中国大陆
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T62328Cabotegravir sodium;化合物 Cabotegravir sodiumCabotegravir sodium
Cabotegravir sodium is a potent inhibitor of HIV integrase and is able to act on HIVADA (IC50: 2.5 nM). cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1 and is less likely to interact with other antiretroviral drugs (ARVs). Antileishmanial agent-12
价 格:¥电议型 号:T62328产 地:中国大陆
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T62327HDAC2-IN-1;化合物 HDAC2-IN-1HDAC2-IN-1
HDAC2-IN-1 (Compound 17) is an orally active, competitive HDAC2 inhibitor (IC50: 0.5 μM) that crosses the blood-brain barrier. HDAC2-IN-1 also inhibits HDAC1 (IC50: 1.61 μM) and HDAC8 (IC50: 0.98 μM).
价 格:¥电议型 号:T62327产 地:中国大陆
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T62326NUCC-0223619;化合物 NUCC-0223619NUCC-0223619
NUCC-0223619 is an IDO1 inhibitor that induces the degradation of IDO protein and can be involved in the synthesis of PROTAC.
价 格:¥电议型 号:T62326产 地:中国大陆
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T62325CXCR7 antagonist-1 hydrochloride;化合物 CXCR7 antagonist-1 hydrochlorideCXCR7 antagonist-1 hydrochlorid
CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of SDF-1 chemokine (also known as CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. hydrochloride can be used for the prevention of tumour cell proliferation, tumour formation, inflammatory diseases and many other diseases.
价 格:¥电议型 号:T62325产 地:中国大陆
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T62324Flibanserin hydrochloride;化合物 Flibanserin hydrochlorideFlibanserin hydrochloride
Flibanserin (BIMT-17; BIMT-17BS) hydrochloride is an orally active 5-HT1A receptor agonist (Ki: 1 nM) and 5-HT2A (Ki: 49 nM) receptor antagonist of 5-hydroxytryptamine. Flibanserin hydrochloride has antidepressant and anxiolytic effects and can be used in studies of hypoactive sexual desire (HSDD).
价 格:¥电议型 号:T62324产 地:中国大陆
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T62323MALT1-IN-5;化合物 MALT1-IN-5MALT1-IN-5
MALT1-IN-5 is a potent inhibitor of the MALT1 protease and can be used in cancer research.
价 格:¥电议型 号:T62323产 地:中国大陆
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T62322(S)-MALT1-IN-5;化合物 (S)-MALT1-IN-5(S)-MALT1-IN-5
(S)-MALT1-IN-5 is a potent inhibitor of MALT1 protease. (S)-MALT1-IN-5 inhibits MALT1 activity and has the potential to improve the enhancement of MALT1 activity caused by abnormal T-cell receptor signalling or B-cell receptor signalling, as well as cancer or inflammatory diseases caused by MALT1 activity. (S)-MALT1-IN-5 has potential for MALT1-related disease studies.
价 格:¥电议型 号:T62322产 地:中国大陆
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T62321ST247;化合物 ST247ST247
ST247 is a potent PPARβ/δ inverse agonist with a high affinity for PPARβ/δ and is able to inversely regulate the expression of the activation marker CCL2. ST247 inhibits agonist-induced transcriptional activity of PPARβ/δ. ST247 efficiently induces interaction with co-repressors.
价 格:¥电议型 号:T62321产 地:中国大陆
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T62320Darifenacin;化合物 DarifenacinDarifenacin
Darifenacin (UK88525) is an M3 muscarinic receptor antagonist (pKi: 8.9).
价 格:¥电议型 号:T62320产 地:中国大陆
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T6232Vilazodone Hydrochloride;盐酸维拉佐酮SB659746A|||EMD 68843|||Vilazodone HCl;盐酸维拉佐酮|||SB659746A|||EMD 68843
Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the major depressive disorder.
价 格:¥电议型 号:T6232产 地:中国大陆