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T6935NirogacestatNirogacestat,γ-secretase,Gamma secretase,cancer,inhibit,PF 3084014,gastrointestinal,toxi
PF-03084014 (PF-3084014) is a specific γ-secretase inhibitor (IC50: 6.2 nM, in a cell-free assay).
价 格：￥电议型 号：T6935产 地：中国大陆
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T8711PF-05186462acute,Na channels,inhibit,chronic,voltage,channel,Na+ channels,Sodium Channel,PF05186462,
PF-05186462 is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.
价 格：￥电议型 号：T8711产 地：中国大陆
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TN2898Kaempferol-7,4’-dimethyl ether
Kaempferol-7,4´-dimethyl ether is isolated from the rhizomes of Zingiber phillipseae and exhibits antioxidant activity against S. aureus and E. coli with MICs at 200 and 225 μg/ml, respectively.
价 格：￥电议型 号：TN2898产 地：中国大陆
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T6514GlasdegibInhibitor,PF 04449913,Glasdegib,inhibit,Smoothened,Smo,PF04449913
Glasdegib (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2.
价 格：￥电议型 号：T6514产 地：中国大陆
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T12433PF-06952229
PF-06952229 is a selective inhibitor of TGFβRI. PF-06952229 can be used in studies about the treatment of solid tumors, specifically metastatic breast cancer.
价 格：￥电议型 号：T12433产 地：中国大陆
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T24626PF-249
PF-249 is a β1-selective AMPK with an EC50 of 12 nM for AMPK α1β1γ1 and can be used in studies about diabetic nephropathy.
价 格：￥电议型 号：T24626产 地：中国大陆
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T28362PF-02413873nonsteroidal,inhibit,PF 2413873,Progesterone Receptor,endometrial,PF-2413873,nuclear,PF 0
PF-02413873 is a competitive antagonist of nonsteroidal progesterone receptor with a Ki of 2.6 nM. PF-02413873 can be used in studies about the treatment of gynecological conditions such as endometriosis.
价 格：￥电议型 号：T28362产 地：中国大陆
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T7343PF-04979064Inhibitor,Phosphoinositide 3-kinase,Mammalian target of Rapamycin,PF 04979064,PF04979064,
PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor(Ki of 0.13 nM and 1.42 nM,respectively).
价 格：￥电议型 号：T7343产 地：中国大陆
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T21738PF-9184PF9184,PF 9184
PF-9184 is a potent and selective inhibitor of human microsomal prostaglandin E synthase-1 (mPGES-1), IC50 =16.5 nM. PF-9184 inhibits IL-1β-induced PGE2 synthesis in vitro.
价 格：￥电议型 号：T21738产 地：中国大陆
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T6341PF04929113PF-04929113；SNX-5422；PF 04929113
SNX-5422 is a synthetic, novel, small molecule Hsp90 Inhibitor. As an oral formulation that demonstrates strong efficacy and tolerability, SNX-5422 is positioned as a breakthrough therapy with broad applicability across a wide range of cancers.
价 格：￥电议型 号：T6341产 地：中国大陆
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T6305SNX2112SNX 2112；PF 04928473；SNX-2112
SNX-2112 is an orally active Hsp90 inhibitor, with a Kd of 16 nM.
价 格：￥电议型 号：T6305产 地：中国大陆
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T6251PF-04691502PF4691502；PF 04691502
PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.
价 格：￥电议型 号：T6251产 地：中国大陆
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T6222PFI-1PFI1；PFI 1；PF-6405761
PFI-1, a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.
价 格：￥电议型 号：T6222产 地：中国大陆
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T6210Pifithrin-μPFTμ；2-Phenylethynesulfonamide；NSC 303580
Pifithrin-μ is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.
价 格：￥电议型 号：T6210产 地：中国大陆
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T6181UPF 1069
UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.
价 格：￥电议型 号：T6181产 地：中国大陆
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T6177PF-562271 besylatePF-00562271 Besylate
PF-562271 (besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
价 格：￥电议型 号：T6177产 地：中国大陆
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T6127Rucaparib Phosphate芦卡帕利；瑞卡帕布磷酸盐；PF-01367338 phosphate；AG-014699；AG-014699 phosphate；PF-01367338
Rucaparib is an inhibitor of PARP (Ki: 1.4 nM for PARP1) that is used in clinical therapy to sensitize cancer cells to chemotherapy.
价 格：￥电议型 号：T6127产 地：中国大陆
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T6043PF-3845PF3845；PF 3845
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.
价 格：￥电议型 号：T6043产 地：中国大陆
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T6042[11C]MP 10Mardepodect；PF-2545920
[11C]MP 10, a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more than1000-fold specificity activity over the PDE.
价 格：￥电议型 号：T6042产 地：中国大陆
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T6028PF 477736PF477736；PF 00477736；PF-477736；PF-736,PF-00477736
PF-477736 is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.
价 格：￥电议型 号：T6028产 地：中国大陆
