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T63716LSD1-IN-18;化合物 LSD1-IN-18LSD1-IN-18
LSD1-IN-18 is a potent, non-covalent, selective inhibitor of LSD1 (Ki:0.156 μM; KD: 0.075 μM).LSD1-IN-18 exhibited anti-proliferative effects in THP-1 leukemia cells and MDA-MB-231 breast cancer cells with IC50 (72 h) of 0.16 and 0.21 μM, respectively.
价 格:¥电议型 号:T63716产 地:中国大陆
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T63715hIgG–hFc receptor-IN-1;化合物 hIgG–hFc receptor-IN-1hIgG–hFc receptor-IN-1
hIgG-hFc receptor-IN-1 is a human immunoglobulin G - human neonatal Fc receptor (hIgG-hFcRn) protein-protein interaction inhibitor (IC50: 2 μM).
价 格:¥电议型 号:T63715产 地:中国大陆
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T63714ATM-IN-1;化合物 ATM-IN-1ATM-IN-1
ATM-IN-1 is a potent inhibitor of ATM. ATM-IN-1 has shown research potential in cancer and neurological diseases.
价 格:¥电议型 号:T63714产 地:中国大陆
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T63708Calpain-2-IN-1;化合物 Calpain-2-IN-1Calpain-2-IN-1
Calpain-2-IN-1 is a selective calpain-2 inhibitor that prolongs ERK activation and thus enhances learning and memory.
价 格:¥电议型 号:T63708产 地:中国大陆
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T63690CDK8-IN-10;化合物 CDK8-IN-10CDK8-IN-10
CDK8-IN-10 is a selective and potent inhibitor of cell cycle protein-dependent kinase (CDK8) (IC50: 8.25 nM) that can be used to study cancer.
价 格:¥电议型 号:T63690产 地:中国大陆
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T63688Isoleucyl tRNA synthetase-IN-1;化合物 Isoleucyl tRNA synthetase-IN-1Isoleucyl tRNA synthetase-IN-1
Isoleucyl tRNA synthetase-IN-1 is a selective and potent inhibitor (Ki: 88 nM) that targets isoleucyl tRNA synthetase (IleRS).
价 格:¥电议型 号:T63688产 地:中国大陆
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T63683Axl-IN-11;化合物 Axl-IN-11Axl-IN-11
Axl-IN-11 is a potent inhibitor of AXL. Axl-IN-11 can be used to study proliferative diseases, allergic diseases, autoimmune diseases, inflammatory diseases, cancer, transplant rejection, viral infectious diseases or other mammalian diseases.
价 格:¥电议型 号:T63683产 地:中国大陆
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T63681DNA Gyrase-IN-1;化合物 DNA Gyrase-IN-1DNA Gyrase-IN-1
DNA Gyrase-IN-1 is a potent and selective DNA promoter inhibitor (IC50: 2.6 μM). DNA Gyrase-IN-1 inhibits Mycobacterium tuberculosis (Mtb) activity well (MIC: 0.49 μM). DNA Gyrase-IN-1 can be used to study tuberculosis.
价 格:¥电议型 号:T63681产 地:中国大陆
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T63680Cap-dependent endonuclease-IN-11;化合物 Cap-dependent endonuclease-IN-11Cap-dependent endonuclease-IN-1
Cap-dependent endonuclease-IN-11 is a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). cap-dependent endonuclease-IN-11 has shown research potential for viral infections.
价 格:¥电议型 号:T63680产 地:中国大陆
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T63673Cap-dependent endonuclease-IN-10;化合物 Cap-dependent endonuclease-IN-10Cap-dependent endonuclease-IN-1
Cap-dependent endonuclease-IN-10 is a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). cap-dependent endonuclease-IN-10 effectively inhibits influenza viruses with low cytotoxicity, good in vivo pharmacokinetic and in vivo pharmacodynamic properties, and good hepatic microsomal stability. Cap-dependent endonuclease-IN-10 has shown investigational potential against viral infections, including influenza A, B and C.
价 格:¥电议型 号:T63673产 地:中国大陆
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T63659HPK1-IN-10;化合物 HPK1-IN-10HPK1-IN-10
HPK1-IN-10 is a potent inhibitor of HPK1, a serine/threonine protein kinase cloned from hematopoietic progenitor cells and a member of the MAP4K family of mammalian Ste-20-associated protein kinases. HPK1-IN-10 has potential for HPK1-related diseases.
价 格:¥电议型 号:T63659产 地:中国大陆
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T63658JAK-IN-18;化合物 JAK-IN-18JAK-IN-18
JAK-IN-18 is a potent inhibitor of JAK and can be used to study a variety of diseases, particularly eye, skin and respiratory diseases.
价 格:¥电议型 号:T63658产 地:中国大陆
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T63656c-Met-IN-11;化合物 c-Met-IN-11c-Met-IN-11
c-Met-IN-11 is a potent inhibitor of c-MET (IC50: 41.4 nM) and VEGFR-2 (IC50: 71.1 nM).
价 格:¥电议型 号:T63656产 地:中国大陆
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T63653AKT-IN-11;化合物 AKT-IN-11AKT-IN-11
AKT-IN-11 is one of the most potent antibacterial agents against human hepatocellular carcinoma Bel-7402 cell line (IC50: 1.15 μM).
价 格:¥电议型 号:T63653产 地:中国大陆
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T63652DHODH-IN-19;化合物 DHODH-IN-19DHODH-IN-19
DHODH-IN-19 is a potent inhibitor of DHODH. DHODH-IN-19 has shown research potential for cancer and inflammatory diseases.
价 格:¥电议型 号:T63652产 地:中国大陆
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T63651IDO1/2-IN-1 hydrochloride;化合物 IDO1/2-IN-1 hydrochlorideIDO1/2-IN-1 hydrochloride
IDO1/2-IN-1 hydrochloride is the first potent dual inhibitor of IDO1 (IC50: 28 nM) and IDO2 (IC50: 144 nM) that is orally active.IDO1/2-IN-1 hydrochloride exhibits antitumor effects.
价 格:¥电议型 号:T63651产 地:中国大陆
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T63647DCN1-UBC12-IN-1;化合物 DCN1-UBC12-IN-1DCN1-UBC12-IN-1
DCN1-UBC12-IN-1 is a potent and specific DCN1-UBC12 inhibitor with an IC50 value of 2.86 nM and anti-cardiac fibrogenic activity.
价 格:¥电议型 号:T63647产 地:中国大陆
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T63628AChE-IN-19;化合物 AChE-IN-19AChE-IN-19
AChE-IN-19 is a potent inhibitor of AChE (IC50: 0.56 μM) and also exhibits inhibition of Aβ aggregation. aChE-IN-19 exhibits neuroprotective effects and is virtually non-toxic to SH-SY5Y cells. aChE-IN-19 can be used to study Alzheimer´s disease.
价 格:¥电议型 号:T63628产 地:中国大陆
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T63623XPO1-IN-1;化合物 XPO1-IN-1XPO1-IN-1
XPO1-IN-1 is an orally active XPO1 inhibitor capable of acting on MM.1S cells (IC50: 24 nM). XPO1-IN-1 effectively induces cell cycle arrest and apoptosis. XPO1-IN-1 exhibits good metabolic stability and pharmacokinetic properties. XPO1-IN-1 can be used to study multiple myeloma.
价 格:¥电议型 号:T63623产 地:中国大陆
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T63618SphK2-IN-1;化合物 SphK2-IN-1SphK2-IN-1
SphK2-IN-1 is an SphK2 inhibitor with an IC50 value of 0.359 μM. SphK2-IN-1 can be used to study cancer, inflammation, neurological and cardiovascular diseases.
价 格:¥电议型 号:T63618产 地:中国大陆