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  • T63614PD-1/PD-L1-IN-15；化合物 PD-1/PD-L1-IN-15PD-1/PD-L1-IN-15

    PD-1/PD-L1-IN-15 is a potent inhibitor of PD-1/PD-L1 (IC50: 60.1 nM) and has shown investigational potential for tumor immunotherapy.

    价 格：￥电议型 号：T63614产 地：中国大陆

  • T63604ATR-IN-18；化合物 ATR-IN-18ATR-IN-18

    ATR-IN-18 is an orally active ATR kinase inhibitor (IC50: 0.69 nM). aTR-IN-18 exhibited anti-proliferative effects in LoVo cells (IC50: 37.34 nM). aTR-IN-18 showed anti-tumor effects.

    价 格：￥电议型 号：T63604产 地：中国大陆

  • T63601PAD2-IN-1 hydrochloride；化合物 PAD2-IN-1 hydrochloridePAD2-IN-1 hydrochloride

    PAD2-IN-1 hydrochloride is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor with superior selectivity for PAD2 over PAD4 (95-fold) and PAD3 (79-fold), and is a benzimidazole-based derivative.

    价 格：￥电议型 号：T63601产 地：中国大陆

  • T63590c-Met-IN-10；化合物 c-Met-IN-10c-Met-IN-10

    c-Met-IN-10 is a potent c-Met kinase inhibitor (IC50: 16 nM). c-Met-IN-10 inhibits the activity of cancer cells A549, H460 and HT-29, and inhibits A549 cell movement by inhibiting HT-29 cell colony formation, which in turn induces apoptosis in HT-29 and A549 cells. c-Met-IN-10 can be used in anticancer studies. -Met-IN-10 is capable of being used in anticancer studies.

    价 格：￥电议型 号：T63590产 地：中国大陆

  • T63586Zika virus-IN-1；化合物 Zika virus-IN-1Zika virus-IN-1

    Zika virus-IN-1 is an inhibitor of Zika virus (EC50: 1.56 μM).

    价 格：￥电议型 号：T63586产 地：中国大陆

  • T63583RET-IN-11；化合物 RET-IN-11RET-IN-11

    RET-IN-11 is a potent and selective RET inhibitor that acts on RET (IC50: 6.20 nM) and RETV804M (IC50: 18.68 nM).RET-IN-11 induces apoptosis.RET-IN-11 exhibits anti-proliferative and migratory effects in LC-2/ad cells. RET-IN-11 showed anti-proliferative and migratory effects in LC-2/ad cells.

    价 格：￥电议型 号：T63583产 地：中国大陆

  • T63579Kallikrein-IN-1；化合物 Kallikrein-IN-1Kallikrein-IN-1

    Kallikrein-IN-1 (Formula A) is an inhibitor of the kinin-releasing enzyme Kallikrein.

    价 格：￥电议型 号：T63579产 地：中国大陆

  • T63574α-Glucosidase-IN-12；化合物 α-Glucosidase-IN-12α-Glucosidase-IN-12

    α-Glucosidase-IN-12 is a potent inhibitor of α-glucosidase (IC50: 10.20 μM).

    价 格：￥电议型 号：T63574产 地：中国大陆

  • T63568PLAP-IN-1；化合物 PLAP-IN-1PLAP-IN-1

    PLAP-IN-1 is a potent and selective PLAP inhibitor with an IC50 value of 32 nM and no significant inhibitory effect on tissue non-specific alkaline phosphatase (TNAP) activity.

    价 格：￥电议型 号：T63568产 地：中国大陆

  • T63565CBP/p300-IN-19 hydrochloride；化合物 CBP/p300-IN-19 hydrochlorideCBP/p300-IN-19 hydrochloride

    CBP/p300-IN-19 hydrochloride is a selective and potent inhibitor of p300/CBP HAT, capable of acting on p300-HAT (IC50: 1.4 μM), CBP-HAT (IC50: 2.2 μM), PCAF (IC50>100 μM), Myst3 (IC50>100 μM). CBP/p300-IN-19 hydrochloride has antitumor effects.

    价 格：￥电议型 号：T63565产 地：中国大陆

  • T63562α-Glucosidase-IN-14；化合物 α-Glucosidase-IN-14α-Glucosidase-IN-14

    α-Glucosidase-IN-14 is a potent inhibitor of α-glucosidase (IC50: 5.22 μM).

    价 格：￥电议型 号：T63562产 地：中国大陆

  • T63557hCA I-IN-1；化合物 hCA I-IN-1hCA I-IN-1

    hCA I-IN-1 is a human carbonic anhydrase I (hCA I) inhibitor that acts on hCA I (Ki: 38.3 nM), hCA II (Ki: 716.4 nM), hCAIX (Ki: 940.1 nM) and hCAXII (Ki: 192.8 nM).

    价 格：￥电议型 号：T63557产 地：中国大陆

  • T63552FtsZ-IN-1；化合物 FtsZ-IN-1FtsZ-IN-1

    FtsZ-IN-1 is a potent FtsZ inhibitor with a quinoline ring and has a strong inhibitory effect on Gram-positive bacteria (MIC: 0.5-8 μg/mL).FtsZ-IN-1 enhances FtsZ polymerization and significantly promotes cell elongation of Bacillus subtilis.FtsZ-IN-1 has low hemolytic toxicity and low FtsZ-IN-1 exhibited anti-drug-resistant bacterial effects due to its low hemolytic toxicity and low tendency to induce drug resistance.

    价 格：￥电议型 号：T63552产 地：中国大陆

  • T63551Glucocorticoid receptor-IN-1；化合物 Glucocorticoid receptor-IN-1Glucocorticoid receptor-IN-1

    Glucocorticoid receptor-IN-1 is a selective regulator of the glucocorticoid receptor (GR) and exhibits anti-inflammatory activity. glucocorticoid receptor-IN-1 has good transcriptional repression, acting on hMMP1 ( IC50: 2.11 nM) and also has a transcriptional activating effect on MMTV (EC50: 5.59 nM).

    价 格：￥电议型 号：T63551产 地：中国大陆

  • T63544RIPK3-IN-1；RIPK3 抑制剂 1RIPK3-IN-1

    RIPK3-IN-1 is a selective and potent RIPK3 inhibitor (IC50: 9.1 nM) that inhibits the activities of c-Met kinase, RIPK1 and RIPK2.RIPK3-IN-1 has potential tumorigenic activity and can be used to study apoptosis.

    价 格：￥电议型 号：T63544产 地：中国大陆

  • T63543HDAC/Top-IN-1；化合物 HDAC/Top-IN-1HDAC/Top-IN-1

    HDAC/Top-IN-1 is a broad-spectrum, orally active dual HDAC/Top inhibitor that acts on HDAC1 (IC50: 0.036 μM), HDAC2 (IC50: 0.14 μM), HDAC3 (IC50: 0.059 μM), HDAC6 (IC50: 0.089 μM) and HDAC8 ( IC50: 9.8 μM). HDAC/Top-IN-1 was able to block HEL cells in S-phase and effectively induce apoptosis.

    价 格：￥电议型 号：T63543产 地：中国大陆

  • T63537SARS-CoV-2 3CLpro-IN-1；化合物 SARS-CoV-2 3CLpro-IN-1SARS-CoV-2 3CLpro-IN-1

    SARS-CoV-2 3CLpro-IN-1 (Compound 14c) is a highly potent inhibitor specifically designed to target and inhibit the activity of SARS-CoV-2 3CL pro, which is a cysteine-protease found in the main coronaviruses. This particular enzyme has been recognized as a highly promising target for the development of effective antiviral drugs. Therefore, SARS-CoV-2 3CLpro-IN-1 holds significant potential for advancing research and development in the field of infectious diseases [1].

    价 格：￥电议型 号：T63537产 地：中国大陆

  • T63536Dual FAAH/sEH-IN-1；化合物Dual FAAH/sEH-IN-1Dual FAAH/sEH-IN-1

    Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.

    价 格：￥电议型 号：T63536产 地：中国大陆

  • T63535Enpp-1-IN-13；化合物 Enpp-1-IN-13Enpp-1-IN-13

    Enpp-1-IN-13 is an ectonucleotide pyrophosphatase/phosphodiesterase (ENPP) inhibitor that is able to act on ENPP1 (IC50: 1.29 μM) and ENPP3 (IC50: 20.2 μM), exhibiting anticancer effects.

    价 格：￥电议型 号：T63535产 地：中国大陆

  • T63531HDAC6/HSP90-IN-1；化合物 HDAC6/HSP90-IN-1HDAC6/HSP90-IN-1

    HDAC6/HSP90-IN-1 is a potent and selective dual inhibitor of HDAC6 (IC50: 4.3 nM) and HSP90 (IC50: 46.8 nM).HDAC6/HSP90-IN-1 downregulates PD-L1 expression in INF-γ-treated H1975 lung cancer cells.HDAC6/HSP90-IN-1 exhibits tumor growth inhibition in H1975 xenograft mice.HDAC6/HSP90-IN-1 is a potent and selective dual inhibitor of HDAC6 (IC50: 4.3 nM) and HSP90 (IC50: 46.8 nM). 1 exhibited tumor growth inhibition in H1975 xenograft mice.

    价 格：￥电议型 号：T63531产 地：中国大陆

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