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T61407TRPC3/6-IN-1;化合物 TRPC3/6-IN-1TRPC3/6-IN-1
TRPC3/6-IN-1 is a highly potent and selective inhibitor that specifically blocks the activity of the canonical transient receptor channels TRPC3 and TRPC6. It exhibits a significant blocking potency against the human isoforms hTRPC3 and hTRPC6, with IC50 values of 1260 nM and 500 nM, respectively. This compound, TRPC3/6-IN-1, is particularly valuable for conducting research on chronic models of heart failure [1].
价 格:¥电议型 号:T61407产 地:中国大陆
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T61406RBM10-8;化合物 RBM10-8RBM10-8
RBM10-8 irreversibly inhibits human sphingosine-1- phosphate lyase (hS1PL) while behaving also as an enzyme substrate.
价 格:¥电议型 号:T61406产 地:中国大陆
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T61405LSD1-IN-14;化合物 LSD1-IN-14LSD1-IN-14
LSD1-IN-14, a powerful and specific inhibitor of LSD1 (with an IC50 value of 0.89 μM), effectively suppresses the growth of A549 and THP-1 cells and promotes the apoptosis of tumor cells [1].
价 格:¥电议型 号:T61405产 地:中国大陆
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T61404α-Synuclein inhibitor 3;化合物 α-Synuclein inhibitor 3α-Synuclein inhibitor 3
α-Synuclein inhibitor 3 (Compound 7g) is a potent inhibitor of α-synuclein (α -Syn) aggregation. It has potential applications in Parkinson´s disease research [1].
价 格:¥电议型 号:T61404产 地:中国大陆
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T61403Plasma kallikrein-IN-3;化合物 Plasma kallikrein-IN-3Plasma kallikrein-IN-3
Plasma kallikrein-IN-3, a potent inhibitor ( IC 50 : 0.15 μM) of plasma kallikrein, finds application in research related to hereditary angioedema, diabetic macular edema, and diabetic retinopathy [1].
价 格:¥电议型 号:T61403产 地:中国大陆
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T61402PGN36;化合物 PGN36PGN36
PGN36 (Compound 18) is a potent and highly selective antagonist of the cannabinoid CB 2 receptor (CB 2 R). It exhibits exceptional affinity for CB 2 R, with a Ki value of 0.09 μM [1].
价 格:¥电议型 号:T61402产 地:中国大陆
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T614013-(3-Phenoxybenzyl)amino-β-carboline;化合物 3-(3-Phenoxybenzyl)amino-β-carboline3-(3-Phenoxybenzyl)amin
3-(3-Phenoxybenzyl)amino-β-carboline is a highly effective tubulin inhibitor, selectively degrading αβ-tubulin heterodimers. It induces cell cycle arrest and apoptosis in the G2/M phase. Additionally, 3-(3-Phenoxybenzyl)amino-β-carboline displays notable anticancer activity [1].
价 格:¥电议型 号:T61401产 地:中国大陆
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T61400Anti-inflammatory agent 9;化合物 Anti-inflammatory agent 9Anti-inflammatory agent 9
Anti-inflammatory agent 9 (compound 28)Anti-inflammatory agent 9 (compound 28) is a benzimidazothiazole derivative derived from tilomisole. It exhibits a higher affinity for the COX-2 enzyme compared to COX-1, thereby demonstrating promising anti-inflammatory properties. Furthermore, it demonstrates oral bioavailability [1].
价 格:¥电议型 号:T61400产 地:中国大陆
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T6140SB-334867 free base;化合物SB-334867SB334867A free base|||SB-334867|||SB 334867|||SB334867;SB334867A fre
SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist.
价 格:¥电议型 号:T6140产 地:中国大陆
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T5032Iguratimod艾拉莫德艾拉莫德|||T614
Iguratimod (T614) is an antirheumatic agent, acts as an inhibitor of COX-2, with an IC50 of 20 μM (7.7 μg/mL), but shows no effect on COX-1. Iguratimod also inhibits macrophage migration inhibitory factor (MIF) with an IC50 of 6.81 μM.
价 格:¥电议型 号:T5032产 地:中国大陆
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T32429KW 2149;化合物 T32429KT6149|||KW2149|||KW-2149;KT6149|||KW2149|||KW-2149
KW 2149 is a compound derived from mitomycin C.
价 格:¥电议型 号:T32429产 地:中国大陆