T21980PD 198306MAPK,inhibit,neuropathic,Inhibitor,MAP2K,rabies,mitogen-activated protein,drug,MAPKK,PD-198

PD 198306 is a selective inhibitor of MAPK/ERK-kinase (MEK) with antihyperalgesic effects. PD 198306 reduces the Streptozocin-induced increase in the level of active ERK1.

价 格：￥电议型 号：T21980产 地：中国大陆

T6470Diclofenac PotassiumApoptosis,Diclofenac Potassium,COX,CHO,caspase,COX-1,cascade,anti-inflammatory,n

Diclofenac potassium is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

价 格：￥电议型 号：T6470产 地：中国大陆

TN1968N-?Feruloyloctopaminecarcinoma,N-?Feruloyloctopamine,inhibit,Protein kinase B,MAPK,PKB,Inhibitor,Hep

N-Feruloyloctopamine is a natural product.

价 格：￥电议型 号：TN1968产 地：中国大陆

TN2081Maohuoside Aorally,MAPK,osteogenesis,Maohuoside A,inhibit,Transforming growth factor beta receptors,

Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.

价 格：￥电议型 号：TN2081产 地：中国大陆

T36010p38 MAPK Inhibitorp-38 MAPK Inhibitor,p38 MAPK Inhibitor

p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.

价 格：￥电议型 号：T36010产 地：中国大陆

T6976SB 239063inhibit,SB 239063,SB-239063,Inhibitor,Autophagy,p38 MAPK

SB239063 is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.

价 格：￥电议型 号：T6976产 地：中国大陆

T9218AndrograpaninInhibitor,chemotaxis,p38 MAPK,leukocyte,SDF-1α,Andrograpanin,PBL,inhibit,Jurkat,anti-in

Andrograpanin is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.

价 格：￥电议型 号：T9218产 地：中国大陆

T9417Lgamma-preprotachykinin amide (72-92) acetategammapreprotachykinin amide (7292) acetate,gamma preprot

gamma-preprotachykinin amide (72-92) acetate is a 21 amino acid peptide belonging to the tachykinin (TK) family and including neurokinin A (NKA) in its C-terminal sequence. gamma-preprotachykinin amide (72-92) acetate possesses higher affinity than NKA for central NK-2 receptors; it shows lower affinity for NK-1 receptors, however, it potently stimulates salivary secretion, which is mediated by NK-1 receptor activation.

价 格：￥电议型 号：T9417L产 地：中国大陆

T6843GDC-0623Mitogen-activated protein kinase kinase,Apoptosis,inhibit,MEK,Inhibitor,MAP2K,MAPKK,MEK inhi

GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.

价 格：￥电议型 号：T6843产 地：中国大陆

T6427ButeinPDE4,Epidermal growth factor receptor,Inhibitor,EGFR,MAPK,ErbB-1,Apoptosis,Autophagy,FoxO3a,in

Butein, a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.

价 格：￥电议型 号：T6427产 地：中国大陆

T6636RefametinibMEK1,allosteric,RDEA 119,BAY-869766,inhibit,Inhibitor,MAP2K,MEK2,orally,MAPKK,RDEA-119,Mi

Refametinib (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM).

价 格：￥电议型 号：T6636产 地：中国大陆

T70515,6,7-TRIMETHOXYFLAVONEp38 MAPK,Inhibitor,5,6,7TRIMETHOXYFLAVONE,inhibit,5,6,7-Trimethoxyflavone,5,6

价 格：￥电议型 号：T7051产 地：中国大陆

T7276SD 0006inhibit,p38 MAPK,SD0006,Autophagy,Inhibitor,SD-0006,SD06,SD 0006,SD 06

SD 0006 is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.

价 格：￥电议型 号：T7276产 地：中国大陆

T6760APS-2-79 hydrochlorideMAP2K,MAPKK,Inhibitor,Mitogen-activated protein kinase kinase,APS 2 79 hydroch

APS-2-79 is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK.

价 格：￥电议型 号：T6760产 地：中国大陆

T6927PamapimodRo-4402257,Autophagy,Inhibitor,IL-6,TNF-α,inhibit,R-1503,IL-1β,p38 MAPK,JNK,Pamapimod,p38β,

Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38 gamma isoforms.

价 格：￥电议型 号：T6927产 地：中国大陆

T7953BpV(HOpic)MAPK/ERK,Phosphatase and tensin homolog,Inhibitor,PTEN,MMAC1,inhibit,PI3K/AKT,BpV(HOpic),s

bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM).

价 格：￥电议型 号：T7953产 地：中国大陆

T9697ASK1-IN-1CNS,inhibit,p38 MAPK,ASK1,ASK-1-IN-1,ASK1 IN 1,ASK1IN1,MAPK,Inhibitor,brain,penetrant

ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays.

价 格：￥电议型 号：T9697产 地：中国大陆

TN1079DeoxyelephantopinAkt,Inhibitor,β-catenin,Deoxyelephantopin,MAPK,Nuclear factor-κB,NF-κB,PI3K,Nuclear

Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling

价 格：￥电议型 号：TN1079产 地：中国大陆

T6S1740Nardosinonecells,Nardosinone,Neurite,substances,PC12D,outgrowth-promoting,neuritogenic,inhibit,MAPK,

1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. 3. Nardosinone enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and stau

价 格：￥电议型 号：T6S1740产 地：中国大陆

T9196IACS-13909antiproliferative,RTK,IACS13909,inhibit,SHP2,pMEK,anticancer,Inhibitor,MAPK,IACS 13909,pER

IACS-13909, a specific and potent allosteric inhibitor of SHP2, that suppresses signaling through the MAPK pathway.

价 格：￥电议型 号：T9196产 地：中国大陆