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  • T70044Sarizotan HCl；Sarizotan 盐酸盐EMD 128130 HCl；EMD 128130 HCl

    Sarizotan HCl (EMD 128130 HCl) is an hERG channel inhibitor and 5-hydroxytryptamine 5-HT1A receptor agonist with potential antidepressant effects for the study of Parkinson´s Dyskinesia.

    价 格：￥电议型 号：T70044产 地：中国大陆

  • T70036AJG-049 HCl；化合物 AJG-049 HClAJG-049 HCl

    AJG-049 HCl is a calcium channel antagonist that inhibits L-type Ca2+ channels via diltiazem-binding site(s).

    价 格：￥电议型 号：T70036产 地：中国大陆

  • T70000Ebopiprant HCl；化合物 Ebopiprant HClEbopiprant HCl

    Ebopiprant, also known as OBE-022, is an Oral and Selective Prostaglandin F 2α Receptor Antagonist as an Effective and Safe Modality for the Treatment of Preterm Labor. OBE022 exhibits potent tocolytic effects on human tissues ex vivo and animal models in vivo without causing the adverse fetal side effects seen with indomethacin.

    价 格：￥电议型 号：T70000产 地：中国大陆

  • T69995Chlorhexidine-d8 HCl；化合物 Chlorhexidine-d8 HClChlorhexidine-d8 HCl

    Chlorhexidine-d8 is intended for use as an internal standard for the quantification of chlorhexidine by GC- or LC-MS. Chlorhexidine is a bis(biguanide) antimicrobial disinfectant and antiseptic agent. It inhibits growth of clinical methicillin-resistant S. aureus (MRSA) isolates (MIC90 = 4 μg/ml). It is also active against canine isolates of MRSA, methicillin-susceptible S. aureus (MSSA), methicillin-resistant S. pseudintermedius (MRSP), and methicillin-susceptible S. pseudintermedius (MSSP; MIC

    价 格：￥电议型 号：T69995产 地：中国大陆

  • T69991Difenamizole HCl；化合物 Difenamizole HClDifenamizole HCl

    Difenamizole HCl is the salt form of Difenamizole, a non-steroidal anti-inflammatory drug (NSAID) and analgesic of the pyrazolone group related to metamizole. It has monoaminergic properties, including inhibition of monoamine oxidase, augmentation of pargyline-induced elevation of striatal dopamine levels, inhibition of K+-induced striatal dopamine release, and inhibition of the reuptake of dopamine.

    价 格：￥电议型 号：T69991产 地：中国大陆

  • T69986BMS-955176 HCl；化合物 BMS-955176 HClBMS-955176 HCl

    GSK-3532795 is a second generation inhibitor of hiv-1 maturation, exhibiting a broader spectrum of antiviral effect in vitro and in clinical studies than the prototypical maturation inhibitor bevirimat

    价 格：￥电议型 号：T69986产 地：中国大陆

  • T69985Lifirafenib HCl；化合物 Lifirafenib HClLifirafenib HCl

    Lifirafenib, also known as Beigene-283, is a Novel potent and selective RAF Kinase and EGFR inhibitor. BGB-283-displays Potent Antitumor Activity in B-RAF Mutated Colorectal Cancers. In vitro, BGB-283 potently inhibits B-RAFV600E-activated ERK phosphorylation and cell proliferation. It demonstrates selective cytotoxicity and preferentially inhibits proliferation of cancer cells harbouring B-RAFV600E and EGFR mutation/amplification. In B-RAFV600E CRC cell lines, BGB-283 effectively inhibits the

    价 格：￥电议型 号：T69985产 地：中国大陆

  • T69978Brostallicin HCl；化合物 Brostallicin HClBrostallicin HCl

    Brostallicin is a synthetic, alpha-bromoacrylic, second-generation minor groove binder (MGB), related to distamycin A, with potential antineoplastic activity. Brostallicin binds to DNA minor groove DNA, after having formed a highly reactive glutathione (GSH)-brostallicin complex in the presence of the enzyme glutathione S-transferase (GST), which is overexpressed in cancer cells; DNA replication and cell division are inhibited, resulting in tumor cell death. Compared to typical MGBs, this agent

    价 格：￥电议型 号：T69978产 地：中国大陆

  • T69973PF-04363467 HCl；化合物 PF-04363467 HClPF-04363467 HCl

    PF-04363467 HCl is a selective dopamine D3/D2 receptor antagonist.

    价 格：￥电议型 号：T69973产 地：中国大陆

  • T69955JPI-547 HCl；化合物 JPI-547 HClJPI-547 HCl

    JPI 547, also known as NOV 1402, is an oral inhibitor of PARP 1/2 and Tankyrase 1/2. JPI-547 demonstrated anti-tumor activity in BRCA-deficient xenograft models as a single-agent and in combination with chemotherapy and immune checkpoint inhibitors.

    价 格：￥电议型 号：T69955产 地：中国大陆

  • T69944NLG802 HCl；化合物 NLG802 HClNLG802 HCl

    NLG802 is an orally bioavailable prodrug of indoximod, a methylated tryptophan, with immune checkpoint inhibitory and antineoplastic activities. Upon oral administration, the indoximod prodrug NLG802 is converted to indoximod. Indoximod targets, binds to and inhibits the enzyme indoleamine 2,3-dioxygenase (IDO; IDO1), which converts the essential amino acid tryptophan into the immunosuppressive metabolite kynurenine. By increasing tryptophan levels and decreasing kynurenine levels, indoximod res

    价 格：￥电议型 号：T69944产 地：中国大陆

  • T69942CN-716 HCl；化合物 CN-716 HClCN-716 HCl

    cn-716 is a novel Zika virus (ZIKV) NS2B-NS3pro protease inhibitor.

    价 格：￥电议型 号：T69942产 地：中国大陆

  • T69934Etoloxamine HCl；化合物 Etoloxamine HClEtoloxamine HCl

    Etoloxamine HCl is the salt form of Etoloxamine free base, a histamine 1 receptor antagonist.

    价 格：￥电议型 号：T69934产 地：中国大陆

  • T69922EPZ020411 HCl；化合物 EPZ020411 HClEPZ020411 HCl

    EPZ020411 is a potent and selective PRMT6 inhibitor tool compound. EPZ020411 shows good bioavailability following subcutaneous dosing in rats making it a suitable tool for in vivo studies. EPZ020411 suppresses RCC1 arginine methylation and improves the cytotoxic activity of radiotherapy against GSC brain tumor xenografts.

    价 格：￥电议型 号：T69922产 地：中国大陆

  • T69908Pidnarulex HCl；化合物 Pidnarulex HClPidnarulex HCl

    Pidnarulex HCl is the salt form of CX-5461, a first-in-class non-genotoxic small molecule targeted inhibitor of RNA polymerase I (Pol I) that activates the p53 pathway without causing DNA damage. CX-5461 selectively inhibits rRNA synthesis by Pol I in the nucleolus, but does not inhibit mRNA synthesis by RNA Polymerase II (Pol II) and does not inhibit DNA replication or protein synthesis. Inhibition of Pol I results in nucleolar stress and release of ribosomal proteins (RP) from the nucleolus. T

    价 格：￥电议型 号：T69908产 地：中国大陆

  • T69905Iferanserin HCl；化合物 Iferanserin HClIferanserin HCl

    Iferanserin HCl is a selective serotonin receptor antagonist.

    价 格：￥电议型 号：T69905产 地：中国大陆

  • T6988SKF 38393 hydrochloride；化合物SKF38393 HCl(±)-SKF-38393 hydrochloride|||SKF-38393A|||SKF38393 HCl；(±)-S

    SKF 38393 hydrochloride (SKF38393 HCl) is a selective dopamine D1/D5 receptor agonist.

    价 格：￥电议型 号：T6988产 地：中国大陆

  • T69862Afeletecan HCl；化合物 Afeletecan HClAfeletecan HCl

    Afeletecan, also known as BAY 56-3722, is a water-soluble camptothecin derivative conjugated to a carbohydrate moiety exhibiting antineoplastic activity. BAY 56-3722 stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. As a consequence of the formation of this complex, both the initial cleavage reaction and religation steps are inhibited and subsequent collision of the replication fork with the cleaved strand of DNA results in inhibition of DNA repli

    价 格：￥电议型 号：T69862产 地：中国大陆

  • T69852CS-003 HCl；化合物 CS-003 HClCS-003 HCl

    CS-003 HCl is a TNRA - triple neurokinin receptor antagonist.

    价 格：￥电议型 号：T69852产 地：中国大陆

  • T69842DB2313 HCl；化合物 DB2313 HClDB2313 HCl

    DB2313 is a first-in-class potent small-molecule inhibitor of PU.1. DB2313 disrupts the interaction of PU.1 with target gene promoters and leads to down-regulation of canonical PU.1 transcriptional targets.

    价 格：￥电议型 号：T69842产 地：中国大陆

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