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T74774Neuraminidase-IN-16；化合物 Neuraminidase-IN-16Neuraminidase-IN-16
Neuraminidase-IN-16 (Compound 43b) serves as a potent inhibitor of neuraminidase, demonstrating IC50 values of 0.031, 0.15, 0.25, 0.60, 0.63, and 10.08 μM against the neuraminidase from H5N1, H5N8, H1N1, H3N2, H5N1–H274Y, and H1N1–H274Y strains, respectively [1].
价 格：￥电议型 号：T74774产 地：中国大陆
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T74766Neuraminidase-IN-12；化合物 Neuraminidase-IN-12Neuraminidase-IN-12
NDV-IN-1 is an antiviral agent with high neuraminidase inhibitory activity. NDV-IN-1 exhibits in vitro inhibitory activity against Newcastle disease virus ( NDV ). NDV-IN-1 significantly inhibits NDV infection of Vero cells by preventing the release of virus particles from infected cells [1] .
价 格：￥电议型 号：T74766产 地：中国大陆
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T74765Viral polymerase-IN-1 hydrochloride；化合物 Viral polymerase-IN-1 hydrochlorideViral polymerase-IN-1 hyd
Viral polymerase-IN-1 hydrochloride, a derivative of Gemcitabine, effectively inhibits influenza A and B virus infections, demonstrating IC90 values ranging from 11.4 to 15.9 μM, and possesses activity against SARS-CoV-2 infection. This compound acts by interfering with viral RNA replication/transcription within cells [1].
价 格：￥电议型 号：T74765产 地：中国大陆
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T74662UBA5-IN-1；化合物 UBA5-IN-1UBA5-IN-1
UBA5-IN-1 (compound 8.5) is a selective inhibitor of UBA5, demonstrating an IC50 of 4.0 μM. It effectively inhibits cell proliferation in Sk-Luci6 cancer cells, which exhibit high expression levels of UBA5 [1].
价 格：￥电议型 号：T74662产 地：中国大陆
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T74630RNA polymerase II-IN-1；化合物 RNA polymerase II-IN-1RNA polymerase II-IN-1
RNA polymerase II-IN-1 (compound 19iv), an amatoxin, selectively inhibits RNA polymerase II (Pol II) with an IC50 of 36.66 nM. It exhibits heightened cytotoxicity towards cancer cells and reduced toxicity in normal cells compared to α-Amanitin [1].
价 格：￥电议型 号：T74630产 地：中国大陆
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T74562Nampt-IN-10 trihydrochloride；化合物 Nampt-IN-10 trihydrochlorideNampt-IN-10 trihydrochloride
Nampt-IN-10 trihydrochloride (Compound 4) is a Nicotinamide Phosphoribosyltransferase (NAMPT) inhibitor exhibiting cellular potency against A2780 and CORL23 cell lines, with IC50 values of 5 nM and 19 nM, respectively. It holds potential as a novel non-antimitotic payload for antibody-drug conjugate (ADC) [1].
价 格：￥电议型 号：T74562产 地：中国大陆
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T74486hCAIX-IN-17；化合物 hCAIX-IN-17hCAIX-IN-17
Compound 6f, also known as hCA IX-IN-1, is a human carbonic anhydrase (hCA) inhibitor that exhibits varying inhibitory effectiveness across different hCA isoforms, with K i values of 331.4 nM for hCA I, 28.4 nM for hCA II, 9.4 nM for hCA IX, and 17.8 nM for hCA XII. It is notable for its anticancer activity [1].
价 格：￥电议型 号：T74486产 地：中国大陆
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T74403NS5A-IN-1；化合物 NS5A-IN-1NS5A-IN-1
NS5A-IN-1 is a proagent of the HCV NS5A inhibitor Pibrentasvir (ABT-530).
价 格：￥电议型 号：T74403产 地：中国大陆
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T74370CDK4/6-IN-11；化合物 CDK4/6-IN-11CDK4/6-IN-11
CDK4/6-IN-11 is a potent PROTAC CDK4/6 degrader.
价 格：￥电议型 号：T74370产 地：中国大陆
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T74360MEK/PI3K-IN-1；化合物 MEK/PI3K-IN-1MEK/PI3K-IN-1
MEK/PI3K-IN-1 (compound 6r) is a potent inhibitor targeting both MEK and PI3K, exhibiting IC50 values of 124 nM for MEK1, 130 nM for PI3Kα, and 236 nM for PI3Kδ. It effectively reduces levels of pAKT and pERK1/2, demonstrating anti-proliferative effects on various tumor cell lines [1].
价 格：￥电议型 号：T74360产 地：中国大陆
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T74294Cap-dependent endonuclease-IN-12；化合物 Cap-dependent endonuclease-IN-12Cap-dependent endonuclease-IN-1
Cap-dependent Endonuclease-IN-12 (EXP-35) is a potent inhibitor of Cap-dependent endonuclease, demonstrating low cytotoxicity. This compound exhibits inhibitory effects on H1N1 [1].
价 格：￥电议型 号：T74294产 地：中国大陆
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T74255HPA-IN-1；化合物 HPA-IN-1HPA-IN-1
HPA-IN-1 (Compound 1) serves as a potent and selective inhibitor of human pancreatic α-amylase (HPA), demonstrating specificity with IC50 values of 12.0 μM for HPA and 410.4 μM for α-glucosidase [1].
价 格：￥电议型 号：T74255产 地：中国大陆
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T74243Tyrosinase/elastase-IN-1；化合物 Tyrosinase/elastase-IN-1Tyrosinase/elastase-IN-1
Tyrosinase/elastase-IN-1, a triterpenoid extracted from the leaves of Rubus fraxinifolius, exhibits inhibitory activities against both tyrosinase and elastase enzymes.
价 格：￥电议型 号：T74243产 地：中国大陆
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T74163TGFβR-IN-1；化合物 TGFβR-IN-1TGFβR-IN-1
TGFβR-IN-1 is a long-acting tumor-activated proagent of a TGFβR inhibitor.
价 格：￥电议型 号：T74163产 地：中国大陆
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T74157Transketolase-IN-1；Transketolase-IN-1Transketolase-IN-1
Transketolase-IN-1 is a promising herbicide candidate for weed control in wheat and maize fields targeting transketolase .
价 格：￥电议型 号：T74157产 地：中国大陆
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T7406AKR1C3-IN-13-(3,4-二氢-1H-异喹啉-2-磺酰基)-苯甲酸3-(3,4-二氢-1H-异喹啉-2-磺酰基)-苯甲酸
AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
价 格：￥电议型 号：T7406产 地：中国大陆
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T73998ADAM8-IN-1；化合物 ADAM8-IN-1ADAM8-IN-1
ADAM8-IN-1 is a potent ADAM8 inhibitor with an IC 50 value of 73 nM.
价 格：￥电议型 号：T73998产 地：中国大陆
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T73995EGFR/CSC-IN-1；化合物 EGFR/CSC-IN-1EGFR/CSC-IN-1
EGFR/CSC-IN-1 is a dual inhibitor targeting both the epidermal growth factor receptor (EGFR [IC50 10.52 nM]) and cancer stem cells (CSC), with potential applications in triple-negative breast cancer research.
价 格：￥电议型 号：T73995产 地：中国大陆
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T73637Dot1L-IN-1 TFA；化合物 Dot1L-IN-1 TFADot1L-IN-1 TFA
Dot1L-IN-1 TFA is a potent and selective Dot1L inhibitor, characterized by a K i of 2 pM and an IC 50 of <0.1 nM. It effectively inhibits H3K79 dimethylation (IC 50 =3 nM) and suppresses the HoxA9 promoter activity (IC 50 =17 nM) in HeLa and Molm-13 cells, respectively [1].
价 格：￥电议型 号：T73637产 地：中国大陆
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T73625αvβ1 integrin-IN-1 TFA；化合物 αvβ1 integrin-IN-1 TFAαvβ1 integrin-IN-1 TFA
αvβ1 Integrin-IN-1 TFA (Compound C8) is a potent, selective inhibitor of αvβ1 integrin, demonstrating an IC 50 value of 0.63 nM. It exhibits antifibrotic effects [1].
价 格：￥电议型 号：T73625产 地：中国大陆
