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T73585PU.1-IN-1；化合物PU.1-IN-1PU.1-IN-1
PU.1-IN-1 is a potent PU.1 inhibitor (IC50 : 2 nM) with anti-inflammatory activity.
价 格：￥电议型 号：T73585产 地：中国大陆
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T7356PTP1B-IN-1；5-苯基-1,2,5-噻二唑烷-3-酮 1,1-二氧化物PTP1B inhibitor；PTP1B inhibitor|||5-苯基-1,2,5-噻二唑烷-3-酮 1,1-二氧化
PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)
价 格：￥电议型 号：T7356产 地：中国大陆
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T73436AK-IN-1；化合物 AK-IN-1AK-IN-1
AK-IN-1, a competitive inhibitor for adenosine (Ado) but not for ATP, demonstrates significant inhibition of AK activity, achieving 86%, 87%, and 89% at concentrations of 2, 4, and 10 ?M, respectively. This compound shows promise for research across various disease areas, such as ischemia, inflammation, and seizures.
价 格：￥电议型 号：T73436产 地：中国大陆
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T73379TMV-IN-1；化合物 TMV-IN-1TMV-IN-1
TMV-IN-1, a chalcone derivative, serves as an inhibitor of the tobacco mosaic virus (TMV), demonstrating effective therapeutic and protective activities, with EC50 values of 70.7 μg/mL and 60.8 μg/mL, respectively. This compound is applicable in research related to infection, inflammation, and tumor [1].
价 格：￥电议型 号：T73379产 地：中国大陆
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T73343BAP1-IN-1；化合物 BAP1-IN-1BAP1-IN-1
BAP1-IN-1 is a catalytic activity inhibitor of BRCA1 associated protein 1 (BAP1), exhibiting an inhibitory concentration (IC50) ranging between 0.1-1 μM.
价 格：￥电议型 号：T73343产 地：中国大陆
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T73325MenA-IN-1；化合物 MenA-IN-1MenA-IN-1
MenA IN-1, a potent inhibitor of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis (MTB), exhibits an IC50 value of 13 ?M and a GIC50 value of 8 ?M, suggesting its potential utility in halting the ongoing proliferation of tuberculosis.
价 格：￥电议型 号：T73325产 地：中国大陆
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T73324PARL-IN-1；化合物 PARL-IN-1PARL-IN-1
PARL-IN-1, a potent PARL inhibitor, exhibits an IC50 value of 28 nM. It effectively inhibits PARL, consequently robustly activating the PINK1/Parkin pathway and promoting PINK1/Parkin-dependent mitophagy.
价 格：￥电议型 号：T73324产 地：中国大陆
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T73322TBK1-IN-1；TBK1 抑制剂 1TBK1-IN-1
TBK1-IN-1 is a specific and potent TANK-binding kinase 1 (TBK1) inhibitor (IC50: 22.4 nM) with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.
价 格：￥电议型 号：T73322产 地：中国大陆
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T73319BTK-IN-19；化合物 BTK-IN-19BTK-IN-19
BTK-IN-19 is a reversible BTK inhibitor with an IC 50 of <0.001 μM [1] .
价 格：￥电议型 号：T73319产 地：中国大陆
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T73318BTK-IN-18；化合物 BTK-IN-18BTK-IN-18
BTK-IN-18 is a potent, reversible inhibitor of Bruton´s tyrosine kinase (BTK) with an inhibitory concentration (IC50) of 0.002 ?M. Additionally, it effectively suppresses CD69 and CD86 expression in vivo.
价 格：￥电议型 号：T73318产 地：中国大陆
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T73310AXL-IN-14；化合物 AXL-IN-14AXL-IN-14
AXL-IN-14 is a potent, orally active inhibitor of AXL with an IC50 of 0.8 nM that effectively suppresses Gas6/AXL-mediated cell migration and invasion, reduces the expression of p-AXL and p-AKT proteins, and demonstrates anti-tumor activity [1].
价 格：￥电议型 号：T73310产 地：中国大陆
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T73303BTK-IN-17；化合物 BTK-IN-17BTK-IN-17
BTK-IN-17 is a selective, orally active inhibitor of Bruton´s Tyrosine Kinase (BTK) with an inhibition concentration (IC50) value of 13.7 nM. It effectively reduces the expression of phosphorylated BTK at Tyrosine 223 (p-BTK Y223) and phosphorylated Phospholipase C Gamma 2 at Tyrosine 1217 (p-PLCγ2 Y1217), demonstrating anti-inflammatory properties.
价 格：￥电议型 号：T73303产 地：中国大陆
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T73300AXL-IN-13；化合物AXL-IN-13AXL-IN-13
AXL-IN-13 is a potent and orally active AXL inhibitor with an IC50 value of 1.6 nM and a Kd value of 0.26 nM.AXL-IN-13 exhibits anticancer activity, reverses TGF-β1-induced epithelial-mesenchymal transition (EMT) and inhibits cancer cell migration and invasion.
价 格：￥电议型 号：T73300产 地：中国大陆
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T73295WNK1-IN-1；化合物 WNK1-IN-1WNK1-IN-1
WNK1-IN-1, a selective inhibitor of WNK1, exhibits an IC50 value of 1.6 μM and also inhibits OSR1 phosphorylation with an IC50 value of 4.3 μM, indicating its potential utility in the research of blood pressure regulation and cancer.
价 格：￥电议型 号：T73295产 地：中国大陆
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T73289mHTT-IN-1；化合物 mHTT-IN-1mHTT-IN-1
mHTT-IN-1 (Example 1) is a potent inhibitor of the mutant huntingtin protein (mHTT), which is toxic and primarily responsible for Huntington´s disease (HD), an inherited autosomal dominant neurodegenerative disorder. This compound effectively reduces mHTT levels with an EC50 of 46 nM.
价 格：￥电议型 号：T73289产 地：中国大陆
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T73274CamA-IN-1；CamA-IN-1CamA-IN-1
CamA-IN-1 is a Clostridioides difficile -specific DNA adenine methyltransferase (CamA) inhibitor. CamA-IN-1 has inhibitory for CamA with IC 50 and K d values of 0.4 μM and 0.2 μM, respectively. CamA-IN-1 can be used for the research of Clostridioides difficile infections (CDI) [1] .
价 格：￥电议型 号：T73274产 地：中国大陆
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T73269CK2α-IN-1；CK2α抑制剂1CK2α-IN-1
CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 ?M and a Ki of 1.6 ?M.CK2α-IN-1 exhibits potential anticancer activity and can be used in cancer research.
价 格：￥电议型 号：T73269产 地：中国大陆
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T73268hRSV-IN-1；化合物 hRSV-IN-1hRSV-IN-1
hRSV-IN-1 is an inhibitor of respiratory syncytial virus (hRSV) [1] [2] .
价 格：￥电议型 号：T73268产 地：中国大陆
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T73261C5aR-IN-1；化合物 C5aR-IN-1C5aR-IN-1
C5aR-IN-1, a potent inhibitor of C5aR, is linked with the potential to research inflammatory diseases. This association is due to the elevated levels of C5a, which are connected with autoimmune and inflammatory disorders.
价 格：￥电议型 号：T73261产 地：中国大陆
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T73256RET-IN-16；化合物 RET-IN-16RET-IN-16
RET-IN-16 is a potent, selective inhibitor of RET, exhibiting IC50 values of 3.98 nM for RET(WT), 8.42 nM for RET(M918T), 15.05 nM for RET(V804L), 7.86 nM for RET(V804M), 5.43 nM for RET-CCDC6, and 8.86 nM for RET-KIF5B, indicating its high efficacy across different RET mutations. It possesses anticancer properties.
价 格：￥电议型 号：T73256产 地：中国大陆
