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T73133FGF22-IN-1；FGF22 抑制剂1FGF22-IN-1
FGF22-IN-1 is a potential CD4 N-terminal immunoglobulin variable region-like domain (CD4 D1) inhibitor.FGF22-IN-1 inhibits the interaction between CD4 and major histocompatibility complex (MHC) class II proteins and suppresses the immune response.
价 格：￥电议型 号：T73133产 地：中国大陆
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T73129STAT6-IN-1；化合物 STAT6-IN-1STAT6-IN-1
STAT6-IN-1, a STAT6 inhibitor, exhibits high affinity for the SH2 domain of STAT6 (IC 50 = 0.028 ?M), making it suitable for research on allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease, or cancer.
价 格：￥电议型 号：T73129产 地：中国大陆
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T73120MptpB-IN-1；化合物 MptpB-IN-1MptpB-IN-1
MptpB-IN-1 is a potent, orally active MptpB inhibitor that targets the Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB), a secreted virulence factor evading host antimicrobial mechanisms. It effectively diminishes the survival and infection burden of multidrug-resistant Mycobacterium tuberculosis.
价 格：￥电议型 号：T73120产 地：中国大陆
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T73111IDO1-IN-17；化合物 IDO1-IN-17IDO1-IN-17
IDO1-IN-17 (I-4) is an IDO1 inhibitor, with an IC 50 of 0.44 μM in hela cells [1] .
价 格：￥电议型 号：T73111产 地：中国大陆
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T73109JNK-1-IN-1；化合物 JNK-1-IN-1JNK-1-IN-1
JNK-1-IN-1 is an inhibitor specifically targeting JNK-1, also exhibiting inhibition of MKK7 with an IC50 value of 7.8μM. It binds to MKK7cp, further reinforcing its role as a JNK-1 inhibitor.
价 格：￥电议型 号：T73109产 地：中国大陆
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T73098BACE2-IN-1；化合物 BACE2-IN-1BACE2-IN-1
BACE2-IN-1, a potent BACE2 inhibitor characterized by its exceptional selectivity and a Ki value of 1.6 nM, is utilized in the investigation of Type 2 Diabetes.
价 格：￥电议型 号：T73098产 地：中国大陆
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T73090EphB1-IN-1；化合物 EphB1-IN-1EphB1-IN-1
EphB1-IN-1 is a potent inhibitor of EphB1, exhibiting IC50 values of 3.0 nM for EphB1 G703C, 15 nM for EphB1 T697G, and 220 nM for EphB1 WT.
价 格：￥电议型 号：T73090产 地：中国大陆
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T73076BACE1-IN-10；化合物 BACE1-IN-10BACE1-IN-10
BACE1-IN-10 is a potent inhibitor of BACE1, demonstrating sub-micromolar activity against recombinant BACE1 (rBACE1) [1].
价 格：￥电议型 号：T73076产 地：中国大陆
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T73070STAT3-IN-14；化合物 STAT3-IN-14STAT3-IN-14
STAT3-IN-14 is a STAT3 inhibitor and has STAT3 phosphorylation inhibitory activity. STAT3-IN-14 can directly bind to the hinge region of STAT3 [1] .
价 格：￥电议型 号：T73070产 地：中国大陆
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T73043HDAC6-IN-15；化合物 HDAC6-IN-15HDAC6-IN-15
HDAC6-IN-15, a selective histone deacetylase 6 (HDAC6) inhibitor, exhibits potent inhibitory activity with an IC50 value of 38.2 nM, making it valuable for research in cancer and neurodegenerative diseases.
价 格：￥电议型 号：T73043产 地：中国大陆
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T73038HSP90-IN-19；化合物 HSP90-IN-19HSP90-IN-19
HSP90-IN-19 is a potent inhibitor of heat shock protein 90 (Hsp90), exhibiting inhibitory activity with an IC50 of 0.27 μM. It is utilized in the research of viral infections, neurodegenerative diseases, and inflammation [1].
价 格：￥电议型 号：T73038产 地：中国大陆
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T73037HSP90-IN-18；化合物 HSP90-IN-18HSP90-IN-18
HSP90-IN-18 is a potent inhibitor of heat shock protein 90 (Hsp90), demonstrating significant inhibitory activity with an IC50 value of 0.39 μM. It is applicable in the research of viral infections, neurodegenerative diseases, and inflammation.
价 格：￥电议型 号：T73037产 地：中国大陆
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T73035STAT3-IN-15；化合物 STAT3-IN-15STAT3-IN-15
STAT3-IN-15, a potent and orally active inhibitor targeting STAT3, effectively combats idiopathic pulmonary fibrosis (IPF) by hindering STAT3 phosphorylation. Additionally, it impedes TGF-β1-induced migration and deformation of epithelial cells and prevents epithelial-mesenchymal transition (EMT), offering a multifaceted approach against IPF.
价 格：￥电议型 号：T73035产 地：中国大陆
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T73034NLRP3-IN-12；化合物 NLRP3-IN-12NLRP3-IN-12
NLRP3-IN-12 is a specific inhibitor of the NLRP3 inflammasome, effectively reducing IL-1β release by targeting the NLRP3 protein, and demonstrating an IC50 of 0.45 μM. This compound is utilized in the research of inflammatory bowel disease.
价 格：￥电议型 号：T73034产 地：中国大陆
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T73033TRK II-IN-1；化合物 TRK II-IN-1TRK II-IN-1
TRK II-IN-1 is a potent type II inhibitor of tropomyosin receptor kinases (TRK), demonstrating inhibitory half-maximal inhibitory concentrations (IC50s) of 3.3, 6.4, 4.3, and 9.4 nM against TRKA, TRKB, TRKC, and the mutant TRKA G667C, respectively. Additionally, this compound exhibits IC50 values of 1.3 nM against FLT3, 9.9 nM against RET, and 71.1 nM against VEGFR2. TRK II-IN-1 primarily serves as a research tool for studying TRK-driven cancers [1].
价 格：￥电议型 号：T73033产 地：中国大陆
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T73032MtInhA-IN-1；化合物 MtInhA-IN-1MtInhA-IN-1
MtInhA-IN-1 is a potent, selective, and orally active inhibitor targeting the Mycobacterium tuberculosis NADH-dependent enoyl-acyl carrier protein reductase (MtInhA), demonstrating an IC50 of 0.23 μM. It exhibits strong efficacy against the M. tuberculosis H37Rv strain, with a MIC value of 0.4 μM.
价 格：￥电议型 号：T73032产 地：中国大陆
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T73031HDAC6-IN-14；化合物 HDAC6-IN-14HDAC6-IN-14
HDAC6-IN-14, an inhibitor of HDAC6 (HDAC), exhibits high selectivity with an IC50 value of 42 nM, demonstrating over 100-fold selectivity compared to HDAC1, HDAC2, HDAC3, and HDAC4.
价 格：￥电议型 号：T73031产 地：中国大陆
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T73030hCAIX-IN-14；化合物 hCAIX-IN-14hCAIX-IN-14
hCAIX-IN-14 is a potent inhibitor of human CA IX with a K i value of 134.8 nM [1] .
价 格：￥电议型 号：T73030产 地：中国大陆
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T73029hCAIX-IN-15；化合物 hCAIX-IN-15hCAIX-IN-15
hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancer activity suitable for cancer research [1].
价 格：￥电议型 号：T73029产 地：中国大陆
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T73028hCAIX-IN-16；化合物 hCAIX-IN-16hCAIX-IN-16
hCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII. It can arrest the cell cycle in the G0-G1 and S phases and induce apoptosis in MDA-MB-468 breast cancer cells. Demonstrating broad-spectrum anticancer activity, hCAIX-IN-16 is a potential tool for cancer research [1].
价 格：￥电议型 号：T73028产 地：中国大陆
