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上海陶术生物科技有限公司 主营产品：生物试剂,实验服务等

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  • T63082IDO1-IN-19；化合物 IDO1-IN-19IDO1-IN-19

    IDO1-IN-19 (Compound 17) is a potent inhibitor of IDO1 and has potential for cancer disease research.

    价 格：￥电议型 号：T63082产 地：中国大陆

  • T63075ALOX15-IN-1；化合物 ALOX15-IN-1ALOX15-IN-1

    ALOX15-IN-1 (compound 8b) is a selective and potent inhibitor of rabbit and human ALOX15 linoleate oxygenase activity, acting on the direct homologues of ALOX15 linoleic acid (LA) (IC50: 0.04 μM) and arachidonic acid (AA) (IC50. 2.06 μM).

    价 格：￥电议型 号：T63075产 地：中国大陆

  • T63073Cap-dependent endonuclease-IN-19；化合物 Cap-dependent endonuclease-IN-19Cap-dependent endonuclease-IN-1

    Cap-dependent endonuclease-IN-19 is a spirocyclic pyridinone derivative and a potent inhibitor of cap-dependent nucleic acid endonuclease (CEN). cap-dependent endonuclease-IN-19 potently inhibits the RNA polymerase activity of influenza A virus.

    价 格：￥电议型 号：T63073产 地：中国大陆

  • T63071CDK6/PIM1-IN-1；化合物 CDK6/PIM1-IN-1CDK6/PIM1-IN-1

    CDK6/PIM1-IN-1 is a balanced, potent, dual CDK6 (IC50: 39 nM) and PIM1 (IC50: 88 nM) inhibitor. CDK6/PIM1-IN-1 showed inhibitory effect on CDK4 with IC50 value of 3.6 nM. CDK6/PIM1-IN-1 can significantly inhibit the proliferation of acute myeloid leukemia (AML) cells, arrest the cell cycle in G1 phase and induce cell apoptosis. CDK6/PIM1-IN-1 showed anti-AML activity.

    价 格：￥电议型 号：T63071产 地：中国大陆

  • T63066ATR-IN-13；化合物 ATR-IN-13ATR-IN-13

    ATR-IN-13 is a potent inhibitor of ATR kinases (IC50: 2 nM) and can be used to study ATR kinase-mediated diseases (e.g. proliferative diseases, cancer).

    价 格：￥电议型 号：T63066产 地：中国大陆

  • T63059CRK12-IN-1；化合物CRK12-IN-1CRK12-IN-1

    CRK12-IN-1 is a potent CRK12 inhibitor.CRK12-IN-1 has insecticidal activity, with inhibitory effects on Trypanosoma brucei (T.b. brucei) and Trypanosoma congolense (T. congolense) with EC50s of 1.3 and 18 nM, respectively.CRK12-IN-1 kills the pathogenic cells rapidly.

    价 格：￥电议型 号：T63059产 地：中国大陆

  • T63058FLT3-IN-14；化合物 FLT3-IN-14FLT3-IN-14

    FLT3-IN-14 is a potent inhibitor of FLT3, acting on FLT3-WT (IC50: 5.6 nM) and FLT3-ITD (IC50: 1.4 nM). FLT3-IN-14 inhibits FLT3 (Y591) phosphorylation, arrests the cell cycle in G1 phase and induces apoptosis.

    价 格：￥电议型 号：T63058产 地：中国大陆

  • T63054CDK9-IN-18；化合物 CDK9-IN-18CDK9-IN-18

    CDK9-IN-18 is a potent inhibitor of CDK9 that blocks the phosphorylation of the kinase CDK9. CDK9-IN-18 exhibits good anticancer activity and low cellular activity and is able to induce apoptosis.

    价 格：￥电议型 号：T63054产 地：中国大陆

  • T63046HPK1-IN-15；化合物 HPK1-IN-15HPK1-IN-15

    HPK1-IN-15 is a selective and effective inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPK1), which was originally cloned from hematopoietic progenitor cells, belongs to the MAP4Ks family. HPK1-IN-15 can be used to study, prevent, or ameliorate diseases or conditions associated with HPK1 activity, such as cancer.

    价 格：￥电议型 号：T63046产 地：中国大陆

  • T63039AKT-IN-13；化合物 AKT-IN-13AKT-IN-13

    AKT-IN-13 (compound 4b) is a potent inhibitor of Akt, acting on Akt1 (IC50: 1.6 nM), Akt2 (IC50: 2.4 nM) and Akt3 (IC50: 0.3 nM). AKT-IN-13 can be used in anticancer research.

    价 格：￥电议型 号：T63039产 地：中国大陆

  • T63037hDHODH-IN-10；化合物 hDHODH-IN-10hDHODH-IN-10

    hDHODH-IN-10 is a selective, orally active, potent hDHODH inhibitor (IC50: 10.9 nM) that forms hydrogen bonds with key residues Arg136 and Gln47. hDHODH-IN-10 inhibits the proliferation of cancer cells and can be used to study cancers (e.g. AML, colon cancer).

    价 格：￥电议型 号：T63037产 地：中国大陆

  • T63034IDO1-IN-13；化合物 IDO1-IN-13IDO1-IN-13

    IDO1-IN-13 (compound 27a) is a potent inhibitor of IDO1 (IC50: 61.6 nM). Ido1-in-13 inhibits cell IDO1 with an EC50 value of 30 nM for HeLa. In SK-OV-3 xenograft tumor tissue, IDO1-IN-13 reduced kyn/trp ratio by 51%.

    价 格：￥电议型 号：T63034产 地：中国大陆

  • T63031PAK1-IN-1；化合物 PAK1-IN-1PAK1-IN-1

    PAK1-IN-1 is a selective and potent inhibitor of PAK1 (IC50: 9.8 nM). PAK1-IN-1 inhibits PAK1-associated tumour cell migration and invasion in a dose-dependent manner.

    价 格：￥电议型 号：T63031产 地：中国大陆

  • T63029TIM-3-IN-1；化合物 TIM-3-IN-1TIM-3-IN-1

    TIM-3-IN-1 is a useful tool to enable further studies on the biology of TIM-3 immunoregulation in cancer.

    价 格：￥电议型 号：T63029产 地：中国大陆

  • T63026JAK-IN-19；化合物 JAK-IN-19JAK-IN-19

    JAK-IN-19 is a potent inhibitor of JAK, with pIC50 values of 7.2 and 7.7 for PBMC IFNγ and HLF Eotaxin, respectively. The pIC50 values for VEGFR2 and Aurora B are 7.0 and 5.8 respectively).

    价 格：￥电议型 号：T63026产 地：中国大陆

  • T63023PTP1B-IN-19；化合物 PTP1B-IN-19PTP1B-IN-19

    PTP1B-IN-19 (Compound 43) is a promising selective benzimidazole derivative as a protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 23.3 μM).PTP1B-IN-17 can be used to study type 2 diabetes.

    价 格：￥电议型 号：T63023产 地：中国大陆

  • T63022PTP1B-IN-18；化合物 PTP1B-IN-18PTP1B-IN-18

    PTP1B-IN-18 is an orally active, fully mixed protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 35.2 μM).PTP1B-IN-18 can be used to study type 2 diabetes.

    价 格：￥电议型 号：T63022产 地：中国大陆

  • T63021PTP1B-IN-17；化合物 PTP1B-IN-17PTP1B-IN-17

    PTP1B-IN-17 (Compound 45) is a selective benzimidazole derivative with potential as a protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 30.2 μM).PTP1B-IN-17 can be used in the study of type 2 diabetes.

    价 格：￥电议型 号：T63021产 地：中国大陆

  • T63015Pancreatic lipase/Carboxylesterase 1-IN-1；化合物 Pancreatic lipase/Carboxylesterase 1-IN-1Pancreatic li

    Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent, dual inhibitor of pancreatic lipase (PL) and human carboxylesterase 1A (hCES1A), acting on PL (IC50: 2.13 μM) and hCES1A (IC50: 0.055 μM).

    价 格：￥电议型 号：T63015产 地：中国大陆

  • T63009NF-κB/PON1-IN-1；化合物 NF-κB/PON1-IN-1NF-κB/PON1-IN-1

    NF-κB/PON1-IN-1 (Compound 16) is an NF-κB/PON1 pathway inhibitor with antioxidant activity (IC50: 45.76 μM) and hepatoprotective activity.

    价 格：￥电议型 号：T63009产 地：中国大陆

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