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  • T63002VEGFR-2-IN-15；化合物 VEGFR-2-IN-15VEGFR-2-IN-15

    VEGFR-2-IN-15 (Compound 14b) is a potent inhibitor of VEGFR-2. VEGFR-2-IN-15 inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis.

    价 格：￥电议型 号：T63002产 地：中国大陆

  • T62999Germination-IN-1；化合物 Germination-IN-1Germination-IN-1

    Germination-IN-1 (compound 11) is a potent germination inhibitor (IC50: 4 μM) with anti-germination effects (germination rate = 14%).

    价 格：￥电议型 号：T62999产 地：中国大陆

  • T62998COX-2/15-LOX-IN-1；化合物 COX-2/15-LOX-IN-1COX-2/15-LOX-IN-1

    COX-2/15-LOX-IN-1 (Compound 14) is a COX-2 and 15-lipoxygenase (15-LOX) inhibitor that acts on COX-1 (IC50: 10.65 μM), COX-2 (IC50: 0.075 μM) and 15-LOX (IC50: 2.98 μM). 25 has an anti-inflammatory effect.

    价 格：￥电议型 号：T62998产 地：中国大陆

  • T62997PI3K/AKT-IN-1；化合物 PI3K/AKT-IN-1PI3K/AKT-IN-1

    PI3K/AKT-IN-1 is a potent, dual PI3K/AKT inhibitor that acts on PI3Kγ (IC50: 6.99 μM), PI3Kδ (IC50: 4.01 μM) and AKT (IC50: 3.36 μM). PI3K/AKT-IN-1 induces caspase 3-dependent apoptosis by inhibiting the PI3K/AKT pathway. caspase 3-dependent apoptosis and exhibited anticancer effects.

    价 格：￥电议型 号：T62997产 地：中国大陆

  • T62994α-Glucosidase-IN-10；化合物 α-Glucosidase-IN-10α-Glucosidase-IN-10

    α-Glucosidase-IN-10 (compound 13) is a potent inhibitor of α-glucosidase (IC50: 92.7 μM). α-Glucosidase-IN-10 can be used to study type II diabetes.

    价 格：￥电议型 号：T62994产 地：中国大陆

  • T62991Mpro/PLpro-IN-1；化合物 Mpro/PLpro-IN-1Mpro/PLpro-IN-1

    Mpro/PLpro-IN-1 (Compound 29) is a dual-acting inhibitor of SARS-CoV-2 protease.Mpro/PLpro-IN-1 is also a potent inhibitor of Mpro/PLpro, with micromolar inhibition of M pro (IC50:1.72 μM) and submicromolar inhibition of PL pro (IC50:0.67 μM). (IC50:0.67 μM).

    价 格：￥电议型 号：T62991产 地：中国大陆

  • T62989IRAK4-IN-12；化合物 IRAK4-IN-12IRAK4-IN-12

    IRAK4-IN-12 (compound 37) is a potent inhibitor of IRAK4 (IC50: 0.015 μM) with cellular pIRAK4 potency (IC50: 0.5 μM).

    价 格：￥电议型 号：T62989产 地：中国大陆

  • T62987iNOs-IN-1；化合物 iNOs-IN-1iNOs-IN-1

    iNOs-IN-1 (YPW) is a potent inhibitor of inducible nitric oxide synthase (iNOS) with anti-inflammatory effects. iNOs-IN-1 significantly inhibits IL-6 and iNOS expression in a dose-dependent manner in murine macrophages, and also inhibits LPS-induced NO generation.

    价 格：￥电议型 号：T62987产 地：中国大陆

  • T62972α-Glucosidase-IN-17；化合物 α-Glucosidase-IN-17α-Glucosidase-IN-17

    α-Glucosidase-IN-17 (Compound 12B) is a potent and orally active inhibitor of α-glucosidase, demonstrating antidiabetic activity with an inhibitory concentration (IC50) of 3.79 μM [1].

    价 格：￥电议型 号：T62972产 地：中国大陆

  • T62971Tubulin polymerization-IN-16；化合物 Tubulin polymerization-IN-16Tubulin polymerization-IN-16

    Tubulin aggregation-IN-16 (compound 5g) is a potent inhibitor of tubulin aggregation. 16 effectively disrupts microtubule/tubulin dynamics and induces cell cycle arrest at G2/M phase in SGC-7901 cells.

    价 格：￥电议型 号：T62971产 地：中国大陆

  • T62970CDK1-IN-1；化合物 CDK1-IN-1CDK1-IN-1

    CDK1-IN-7 is a potent inhibitor of CDK1 with an IC50 value of 161.2 nM for CDK1/CycB. CDK1-IN-7 induces apoptosis in a p53-dependent manner via the apoptosis-intrinsic pathway. CDK1-IN-7 selectively acts on tumour tissue and has potential anti-proliferative effects. CDK1-IN-7 is a potential CDK1-IN-7 is a potential targeted anti-tumour agent.

    价 格：￥电议型 号：T62970产 地：中国大陆

  • T62954Ferroportin-IN-1；化合物 Ferroportin-IN-1Ferroportin-IN-1

    Ferroportin-IN-1 is an inhibitor of the iron transport protein ferroportin and can be used to study diseases such as thalassaemia, sickle cell disease and haemochromatosis due to iron deficiency or disorders of iron metabolism.

    价 格：￥电议型 号：T62954产 地：中国大陆

  • T62950IRAK4-IN-18；化合物 IRAK4-IN-18IRAK4-IN-18

    IRAK4-IN-18 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) (IC50: 15 nM). IRAK4-IN-18 inhibits LPS-induced IL23 production in THP and DC cells and blocks the development of arthritis in rats, a model of arthritis. IRAK4-IN-18 can be used to study arthritic diseases.

    价 格：￥电议型 号：T62950产 地：中国大陆

  • T62948PI3Kβ-IN-1；化合物 PI3Kβ-IN-1PI3Kβ-IN-1

    PI3Kβ-IN-1 is a selective, orally active PI3Kβ inhibitor (IC50: 2 nM).

    价 格：￥电议型 号：T62948产 地：中国大陆

  • T62947Lp-PLA2-IN-11；化合物 Lp-PLA2-IN-11Lp-PLA2-IN-11

    Lp-PLA2-IN-11 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2-IN-11 has the potential to be investigated in diseases associated with Lp-PLA2 activity (e.g. atherosclerosis, Alzheimer´s disease).

    价 格：￥电议型 号：T62947产 地：中国大陆

  • T62945Aurora A/PKC-IN-1；化合物 Aurora A/PKC-IN-1Aurora A/PKC-IN-1

    Aurora A/PKC-IN-1 (Compound 2e) is a potent dual inhibitor of Aurora A (AurA) and PKC (α, β1, β2, θ), acting on AurA (IC50: 6.9 nM) and PKCα (IC50: 16.9 nM). Aurora A/PKC-IN-1 showed anti-proliferative and anti-metastatic effects on breast cancer cells.

    价 格：￥电议型 号：T62945产 地：中国大陆

  • T62926CDK7/12-IN-1；化合物 CDK7/12-IN-1CDK7/12-IN-1

    CDK7/12-IN-1 is a selective inhibitor of CDK7/12, acting on CDK7 (IC50: 3 nM) and CDK 12 (IC50: 277 nM). Inhibition of CDK7 and CDK12 is an effective inhibitor of tumour growth.

    价 格：￥电议型 号：T62926产 地：中国大陆

  • T62919CDK9-IN-13；化合物 CDK9-IN-13CDK9-IN-13

    CDK9-IN-13 is a potent and selective CDK inhibitor (IC50<3 nM). CDK9-IN-13 has a very short half-life in rodents.

    价 格：￥电议型 号：T62919产 地：中国大陆

  • T62905GLS-1-IN-1；化合物 GLS-1-IN-1GLS-1-IN-1

    GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.

    价 格：￥电议型 号：T62905产 地：中国大陆

  • T62899Tau-aggregation and neuroinflammation-IN-1；Tau蛋白聚集体和神经炎症抑制剂1Tau-aggregation and neuroinflammation-IN

    Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-length tau protein aggregates. Tau-aggregation and neuroinflammation-IN-1 has anti-inflammatory activity and reduces NO release.Tau-aggregation and neuroinflammation-IN-1 has low cytotoxicity against LSP-stimulated BV2 cells.Tau-aggregation and neuroinflammation-IN-1 reverses okadaic acid-induced memory impairment in rats.

    价 格：￥电议型 号：T62899产 地：中国大陆

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