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  • T62555MMP-2/9-IN-1；化合物 MMP-2/9-IN-1MMP-2/9-IN-1

    MMP-2/9-IN-1 (Compound 4a) is a potent dual inhibitor of MMP-2 (IC50: 56 nM) and MMP-9 (IC50: 38 nM). leading to DNA fragmentation.

    价 格：￥电议型 号：T62555产 地：中国大陆

  • T62548ATR-IN-17；化合物 ATR-IN-17ATR-IN-17

    ATR-IN-17 is a potent inhibitor of ATR kinase with good anti-cancer effects in LoVo cells (IC50: 1 nM).

    价 格：￥电议型 号：T62548产 地：中国大陆

  • T62547HPK1-IN-17；化合物 HPK1-IN-17HPK1-IN-17

    HPK1-IN-17 is a selective and potent inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPK1) is a member of the MAP4Ks family and was originally cloned from hematopoietic progenitor cells. HPK1-IN-17 can be used to study, prevent or ameliorate diseases or conditions associated with HPK1 activity (e.g., cancer).

    价 格：￥电议型 号：T62547产 地：中国大陆

  • T62538AChE-IN-15；化合物 AChE-IN-15AChE-IN-15

    AChE-IN-15 (Compound 3d) is a reversible inhibitor of human acetylcholinesterase (huAChE) and human butyrylcholinesterase (huBChE) with IC50 values of 6.8 μM and 16.1 μM for huAChE and huBChE, respectively, with significant antioxidant activity. Alzheimer´s disease.

    价 格：￥电议型 号：T62538产 地：中国大陆

  • T62536S100P-IN-1；S100P抑制剂1S100P-IN-1

    S100P-IN-1 is a potent S100P inhibitor.S100P-IN-1 has anti-metastatic effects on pancreatic cancer (pancreatic) cells.

    价 格：￥电议型 号：T62536产 地：中国大陆

  • T62531TRK-IN-12；化合物 TRK-IN-12TRK-IN-12

    TRK-IN-12 (Compound 9e), a macrocyclic derivative, is a potent TRK inhibitor, with efficacy against TRK G595R (IC 50 = 13.1 nM). It demonstrates significant antiproliferative activity in the Ba/F3-LMNA-NTRK1 cell line (IC 50 = 0.080 μM) and exhibits superior inhibitory performance (IC 50 = 0.646 μM) compared to the control agent LOXO-101 in the Ba/F3-LMNA-NTRK1-G595R cell line [1].

    价 格：￥电议型 号：T62531产 地：中国大陆

  • T62521A2AAR/HDAC-IN-1；化合物 A2AAR/HDAC-IN-1A2AAR/HDAC-IN-1

    A2AAR/HDAC-IN-1 (compound 14c) is an orally active, balanced A2AAR/HDAC dual inhibitor of A2AAR (Ki: 163.5 nM), HDAC1 (IC50: 145.3 nM). effect.

    价 格：￥电议型 号：T62521产 地：中国大陆

  • T62518GRK6-IN-1；化合物 GRK6-IN-1GRK6-IN-1

    GRK6-IN-1 (compound 18) is a potent inhibitor of G protein-coupled receptor kinase 6 (GRK6) (IC50: 120 nM). GRK6-IN-1 has the potential to be studied in multiple myeloma.

    价 格：￥电议型 号：T62518产 地：中国大陆

  • T62508PARP-1/2-IN-1；化合物 PARP-1/2-IN-1PARP-1/2-IN-1

    PARP-1-/2-IN-1 is a potent inhibitor of PARP-1 (IC50: 0.51 nM) and PARP-2 (IC50: 23.11 nM).

    价 格：￥电议型 号：T62508产 地：中国大陆

  • T62503EGFR/BRAFV600E-IN-1；化合物 EGFR/BRAFV600E-IN-1EGFR/BRAFV600E-IN-1

    EGFR/BRAFV600E-IN-1 (Compound 23) is a potent dual inhibitor of EGFR (IC50: 0.08 μM) and BRAFV600E (IC50: 0.15 μM). EGFR/BRAFV600E-IN-1 exhibited anti-proliferative effects on A-549 (IC50: 1.2 μM), MCF-7 (IC50: 0.79 μM), Panc-1 (IC50: 1.3 μM), HT-29 (IC50: 1.23 μM).

    价 格：￥电议型 号：T62503产 地：中国大陆

  • T62501PD-1/PD-L1-IN-17；化合物 PD-1/PD-L1-IN-17PD-1/PD-L1-IN-17

    PD-1/PD-L1-IN-17 (Compound P20) is a potent PD-1/PD-L1 inhibitor (IC50: 26.8 nM). PD-1/PD-L1-IN-17 is a promising lead compound for the development of inhibitors of PD-1/PD-L1 interactions. -17 has potential for cancer disease research.

    价 格：￥电议型 号：T62501产 地：中国大陆

  • T62499RIPK1-IN-14；化合物 RIPK1-IN-14RIPK1-IN-14

    RIPK1-IN-14 (Compound 41) is a potent inhibitor of RIPK1 (IC50: 92 nM).RIPK1-IN-14 has a significant anti-necrotic apoptotic effect in a model of necrotic apoptosis in U937 cells.

    价 格：￥电议型 号：T62499产 地：中国大陆

  • T62491STAT3-IN-13；STAT3抑制剂13STAT3-IN-13

    STAT3-IN-13 is a potent STAT3 inhibitor.STAT3-IN-13 has antiproliferative and anticancer activity and acts by binding to the structural domain of STAT3 SH2.STAT3-IN-13 inhibits the phosphorylation of STAT3 Y705, which induces apoptosis and inhibits tumor cell growth and metastasis.STAT3-IN-13 can be used to study breast cancer and liver cancer. The study of breast cancer and hepatocellular carcinoma.

    价 格：￥电议型 号：T62491产 地：中国大陆

  • T62487HER2-IN-12；化合物 HER2-IN-12HER2-IN-12

    HER2-IN-12 is an HER2 inhibitor with an IC50 value of 121 nM and can be used to study cancers such as breast cancer.

    价 格：￥电议型 号：T62487产 地：中国大陆

  • T62486VIM-2-IN-1；化合物 VIM-2-IN-1VIM-2-IN-1

    VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activity. IC50: 48 μM) and New Delhi Metal (NDM-1) (IC50: 231 μM).

    价 格：￥电议型 号：T62486产 地：中国大陆

  • T62485FabG1-IN-1；化合物 FabG1-IN-1FabG1-IN-1

    FabG1-IN-1 (Compound 29) is a potent inhibitor of MabA (FabG1) (IC50: 38 μM).

    价 格：￥电议型 号：T62485产 地：中国大陆

  • T624793CPLro-IN-1；化合物 3CPLro-IN-13CPLro-IN-1

    3CPLro-IN-1 (compound A17) is a potent, orally active inhibitor of SARS-CoV-2 3CLpro (IC50: 5.65 μM). 3-Chymotrypsin-like cysteine protease (3CLpro), a protein essential for viral replication, is an attractive drug target against COVID-19. Antitumor agent-51

    价 格：￥电议型 号：T62479产 地：中国大陆

  • T62477Tubulin polymerization-IN-18；化合物 Tubulin polymerization-IN-18Tubulin polymerization-IN-18

    Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.

    价 格：￥电议型 号：T62477产 地：中国大陆

  • T62474JS1310；化合物 JS1310PRMT7-IN-1|||JS-1310；PRMT7-IN-1|||JS-1310

    JS1310 is a selective PRMT7 inhibitor (IC50: 5 μM against human PRMT7). JS1310 has shown anti-cancer effects on different cancer cells.

    价 格：￥电议型 号：T62474产 地：中国大陆

  • T62467HBV-IN-18；化合物 HBV-IN-18HBV-IN-18

    HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).

    价 格：￥电议型 号：T62467产 地：中国大陆

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