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T62130IDO-IN-16;化合物 IDO-IN-16IDO-IN-16
IDO-IN-16 (compound 5) is an IDO inhibitor (IC50: 36 nM).
价 格:¥电议型 号:T62130产 地:中国大陆
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T62127AMPA-IN-1;化合物 AMPA-IN-1AMPA-IN-1
AMPA-IN-1 is a potent inhibitor of AMPA receptors, a widely expressed receptor in the brain with a central role in the regulation of rapid excitatory synaptic transmission and synaptic plasticity. 14).
价 格:¥电议型 号:T62127产 地:中国大陆
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T62114JAK3-IN-12;化合物 JAK3-IN-12JAK3-IN-12
JAK3-IN-12 (compound 15k) is a potent inhibitor of JAK3 (IC50: 9.5 nM) and can be used in the study of rheumatoid arthritis.
价 格:¥电议型 号:T62114产 地:中国大陆
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T62103COX-2/PI3K-IN-1;化合物 COX-2/PI3K-IN-1COX-2/PI3K-IN-1
COX-2/PI3K-IN-1 (compound 5d) is a potent inhibitor of PI3K (IC50: 1.14 nM). COX-2/PI3K-IN-1 is a selective inhibitor of COX-2 (Ki: 3.24 nM).
价 格:¥电议型 号:T62103产 地:中国大陆
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T62099LSD1-IN-13;化合物 LSD1-IN-13LSD1-IN-13
LSD1-IN-13 (compound 7e) is an orally active LSD1 inhibitor (IC50: 24.43 nM) that also activates CD86 expression (EC50: 470 nM).LSD1-IN-13 induces differentiation of AML (acute myeloid leukaemia) cell lines.
价 格:¥电议型 号:T62099产 地:中国大陆
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T62096Dyrk1A/α-synuclein-IN-1;化合物 Dyrk1A/α-synuclein-IN-1Dyrk1A/α-synuclein-IN-1
Dyrk1A/α-synuclein-IN-1 (Compound b1) is a dual inhibitor of Dyrk1A (IC50: 177 nM) and α-synuclein aggregation (IC50: 10.5 μM). CNS permeability and neuroprotective activity.
价 格:¥电议型 号:T62096产 地:中国大陆
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T62095TRK-IN-19;化合物 TRK-IN-19TRK-IN-19
TRK-IN-19 (Compound I-10 ) is a potent inhibitor of TRK with IC50 values of 1.1 nM for TRKA and 5.3 nM for TRKAG595R. TRK-IN-19 has shown potential research value in cancer disease.
价 格:¥电议型 号:T62095产 地:中国大陆
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T62093Trk-IN-11;化合物 Trk-IN-11Trk-IN-11
Trk-IN-11 (Compound 14h) is a potent inhibitor of TRK, with IC50 values of 1.4 nM for TrkA and 1.8 nM for TrkA G595R. Trk-IN-11 has shown research potential in cancer diseases.
价 格:¥电议型 号:T62093产 地:中国大陆
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T62078Akt/NF-κB/JNK-IN-1;化合物 Akt/NF-κB/JNK-IN-1Akt/NF-κB/JNK-IN-1
Akt/NF-κB/JNK-IN-1 (Compound 2i) is an inhibitor of Akt, NF-κB and JNK signalling pathways.Akt/NF-κB/JNK-IN-1 exhibits an inhibitory effect on nitric oxide production (IC50: 3.15 μM) and shows anti-inflammatory effects.
价 格:¥电议型 号:T62078产 地:中国大陆
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T62075HSV-1/HSV-2-IN-1;化合物 HSV-1/HSV-2-IN-1HSV-1/HSV-2-IN-1
HSV-1/HSV-2-IN-1 is an HSV-1 and HSV-2 inhibitor that acts against HSV-1 (KOS) (EC50: 7.6 μM), HSV-2 (G) (EC50: 7.6 μM), HSV-1 TK-KOS ACVr (EC50: 4 μM) and cowpox virus (EC50: 12 μM).
价 格:¥电议型 号:T62075产 地:中国大陆
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T62071VEGFR-2-IN-16;化合物 VEGFR-2-IN-16VEGFR-2-IN-16
VEGFR-2-IN-16 (Compound 15b) is a potent inhibitor of VEGFR-2 (IC50: 86.36 nM) that exhibits antitumour effects.
价 格:¥电议型 号:T62071产 地:中国大陆
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T62058αβ-Tubulin-IN-1;化合物 αβ-Tubulin-IN-1αβ-Tubulin-IN-1
αβ-Tubulin-IN-1 is a potent and orally active inhibitor of αβ-Tubulin. αβ- Tubulin-IN-1 blocks cell cycle at G2/M phase and induces apoptosis. αβ-Tubulin-IN-1 inhibits tumor cell migration and metastasis. αβ-Tubulin-IN-1 exhibits significant antitumor efficacy.
价 格:¥电议型 号:T62058产 地:中国大陆
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T62048Topo I-IN-1;化合物 Topo I-IN-1Topo I-IN-1
Topo I-IN-1 (Compound 14d) is a potent Topo I inhibitor. Topo I-IN-1 exhibits antitumor activity and DNA intercalative capability. Topo I-IN-1 can induce cell apoptosis.
价 格:¥电议型 号:T62048产 地:中国大陆
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T62047pan-HER-IN-1;化合物 pan-HER-IN-1pan-HER-IN-1
pan-HER-IN-1 (Compound C5) is an irreversible, orally active pan- HER inhibitor. pan-HER-IN-1 exhibits IC 50s of 0.38, 1.6, 2.2 and 3.5 nM for EGFR, HER4, EGFR T790M/L858R and HER2, respectively. pan-HER-IN-1 induces apoptosis and exhibits antitumor activities.
价 格:¥电议型 号:T62047产 地:中国大陆
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T62043Dyrk1A/B-IN-1;化合物 Dyrk1A/B-IN-1Dyrk1A/B-IN-1
Dyrk1A/B-IN-1 (compound 3n) is a potent, selective and cell-permeable inhibitor of DYRK1A and DYRK1B. Dyrk1A/B-IN-1 inhibits DYRK1A and DYRK1B with Kis of 67.8 nM and 237.9 nM, and IC 50 s of 1.1 μM and 0.8 μM, respectively.
价 格:¥电议型 号:T62043产 地:中国大陆
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T62030BRD4-BD1-IN-1;化合物 BRD4-BD1-IN-1BRD4-BD1-IN-1
BRD4-BD1-IN-1 (Compound 9a) is a BRD4-BD1 inhibitor(IC50= 38.20 μM).
价 格:¥电议型 号:T62030产 地:中国大陆
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T62026hCAIX-IN-11;化合物 hCAIX-IN-11hCAIX-IN-11
hCAIX-IN-11 (Compound 5d) is a selective carbonic anhydrase IX and XII inhibitor. hCAIX-IN-11 shows K i s of 32.7 and 623.5 nM for hCA IX and hCA XII, respectively.
价 格:¥电议型 号:T62026产 地:中国大陆
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T62015PqsR/LasR-IN-1;化合物 PqsR/LasR-IN-1PqsR/LasR-IN-1
PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of LasR and PqsR systems in P. aeruginosa. PqsR/LasR-IN-1 is also a inhibitor of hERG (IC50= 6.77 μM).
价 格:¥电议型 号:T62015产 地:中国大陆
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T62013PI3Kδ-IN-10;化合物 PI3Kδ-IN-10PI3Kδ-IN-10
PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50= 2 nM). In hepatocellular carcinoma models, PI3Kδ-IN-10 robustly suppresses the downstream AKT pathway to induce subsequent apoptosis.
价 格:¥电议型 号:T62013产 地:中国大陆
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T62003SOS1-IN-13;化合物 SOS1-IN-13SOS1-IN-13
SOS1-IN-13 is a potent inhibitor of son of sevenless homolog 1 (SOS1). SOS1-IN-13 shows IC 50 s of 6.5 nM and 327 nM for SOS1 and pERK, respectively. SOS1-IN-13 has research value in anticancer.
价 格:¥电议型 号:T62003产 地:中国大陆