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T61984MtMetAP1-IN-1；化合物 MtMetAP1-IN-1MtMetAP1-IN-1
MtMetAP1-IN-1 is an inhibitor of methionine aminopeptidase 1 ( MetAP1 ). MtMetAP1-IN-1 shows antimycobacterial activity.
价 格：￥电议型 号：T61984产 地：中国大陆
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T61981Human carbonic anhydrase II-IN-1；化合物 Human carbonic anhydrase II-IN-1Human carbonic anhydrase II-IN-
Human carbonic anhydrase II-IN-1 (Compound S-13) is a potent human carbonic anhydrase II (hCA II) inhibitor. Human carbonic anhydrase II-IN-1 shows Kis of 4.4 nM, 9.2 nM, 480.2 nM and 14.7 nM for hCA II, I, IV and IX, respectively. Human carbonic anhydrase II-IN-1 can be used for glaucoma research.
价 格：￥电议型 号：T61981产 地：中国大陆
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T61977FLT3/D835Y-IN-1；化合物 FLT3/D835Y-IN-1FLT3/D835Y-IN-1
FLT3/D835Y-IN-1 (compound 13a) is a orally active, and selective inhibitor of FLT3 and FLT3/D835Y, with IC50s of 0.26 nM and 0.18 nM, respectively. FLT3/D835Y-IN-1 has anticancer efficacy, and has research value in AML (acute myeloid leukemia).
价 格：￥电议型 号：T61977产 地：中国大陆
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T61969AChE/BChE-IN-10；化合物AChE/BChE-IN-10AChE/BChE-IN-10
AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation.
价 格：￥电议型 号：T61969产 地：中国大陆
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T61965SphK1-IN-1；化合物 SphK1-IN-1SphK1-IN-1
SphK1-IN-1 is an inhibitor of SphK1 with anti-tumor activity. SphK1-IN-1 inhibits the ATPase of SphK1, IC50=2.48 μM. SphK1-IN-1 has the value of cancer research.
价 格：￥电议型 号：T61965产 地：中国大陆
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T61962PARP-1/HDAC-IN-1；化合物 PARP-1/HDAC-IN-1PARP-1/HDAC-IN-1
PARP-1/HDAC-IN-1 is an effective dual inhibitor of PARP-1/HDAC6, with IC50 of 68.90 nM and 510 nM respectively. PARP-1/HDAC-IN-1 has anti-cancer, anti-migration and anti-angiogenesis activities.
价 格：￥电议型 号：T61962产 地：中国大陆
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T61958MAO A/HDAC-IN-1；化合物 MAO A/HDAC-IN-1MAO A/HDAC-IN-1
MAO A/HDAC-IN-1 is an effective monoamine oxidase A (MAO A) and HDAC dual inhibitor, which can be used for glioma research.
价 格：￥电议型 号：T61958产 地：中国大陆
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T61956BACE1/2-IN-1；化合物 BACE1/2-IN-1BACE1/2-IN-1
BACE1/2-IN-1 (compound 34) is an effective BACE1 and BACE2 inhibitor with IC50 of 0.01 and 0.0053 μM, respectively. BACE1/2-IN-1 has lower Pgp efflux ratio and improved passive permeability. The metabolic stability of BACE1/2-IN-1 in liver microsomes is decreased.
价 格：￥电议型 号：T61956产 地：中国大陆
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T61946IMP2-IN-1；化合物 IMP2-IN-1IMP2-IN-1
IMP2-IN-1 (compound 4) is an effective IMP2 inhibitor with an IC50 of 81.3-127.5 μM for IMP2 RNA . IMP2-IN-1 decreased the level of IMP2 in SW480 cells. IMP2-IN-1 significantly inhibited the activity of differentiated and undifferentiated Huh7 cells.
价 格：￥电议型 号：T61946产 地：中国大陆
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T61945hGGPPS-IN-1；化合物 hGGPPS-IN-1hGGPPS-IN-1
HGGPPS-IN-1 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). HGGPPS-IN-1 has an effective inhibitory effect on human geranyl geranyl pyrophosphate synthase (hGGPPS). HGGPPS-IN-1 can selectively induce apoptosis of multiple myeloma (MM) cells. HGGPPS-IN-1 showed anti-myeloma activity in vivo.
价 格：￥电议型 号：T61945产 地：中国大陆
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T61944IDO1-IN-15；化合物 IDO1-IN-15IDO1-IN-15
IDO1-IN-15 is an effective IDO1 inhibitor with IC50 of 127 nM. The potency of IDO1-IN-15 against IDO1 enzyme is comparable with Epacadostat in vitro.
价 格：￥电议型 号：T61944产 地：中国大陆
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T61939Topo I/COX-2-IN-1；化合物 Topo I/COX-2-IN-1Topo I/COX-2-IN-1
Topo I/COX-2-IN-1 (1H-30) is a potent Topo I/COX-2 inhibitor with the IC50 of 0.24 μM and 4.42 μM for COX-2 and Topo I, respectively. Topo I/COX-2-IN-1 induces apoptosis and inhibits migration of cancer cells, shows anti-cancer activity.
价 格：￥电议型 号：T61939产 地：中国大陆
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T61938HSP90-IN-12；化合物 HSP90-IN-12HSP90-IN-12
Vibsanin A analog C (VAC) is an anti-cancer compound, which shows anti-proliferative effect on various cancer cell lines, and the anti-proliferative activity is the strongest among vibsanin A analogues. VAC fluctuated the amount of HSP90-related proteins in cells and showed an inhibitory effect on HSP90-mediated luciferase refolding in vitro.
价 格：￥电议型 号：T61938产 地：中国大陆
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T61931IRAK4-IN-10；化合物 IRAK4-IN-10IRAK4-IN-10
IRAK4-IN-10 (compound 75) is an effective IRAK4 inhibitor (IC50 is 1.5 nM), which can block the MyD88-dependent signal pathway. IRAK4-IN-10 has research potential in inflammatory diseases, autoimmune diseases and cancer.
价 格：￥电议型 号：T61931产 地：中国大陆
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T61929PD-1/PD-L1-IN-14；化合物 PD-1/PD-L1-IN-14PD-1/PD-L1-IN-14
PD-1/PD-L1-IN-14 (compound 17) is an inhibitor of PD-1/PD-L1 interaction (IC50=27.8 nM). By inhibiting the interaction of PD-1/PD-L1, PD-1/PD-L1-IN-14 promotes dimerization, endocytosis and degradation of PD-L1.
价 格：￥电议型 号：T61929产 地：中国大陆
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T61922CDK7-IN-12；化合物 CDK7-IN-12CDK7-IN-12
CDK7-IN-12 is an effective CDK7 inhibitor and plays a key role in regulating transcription and cell cycle. CDK7-IN-12 can effectively inhibit the proliferation of malignant tumors in vitro and in vivo. CDK7-IN-12 has research potential in cancer diseases.
价 格：￥电议型 号：T61922产 地：中国大陆
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T61906POP-IN-1；化合物 POP-IN-1POP-IN-1
POP-IN-1 (Compound 12h) is an effective POP inhibitor (Ki=0.009 μM）. POP-IN-1 has research potential in neurodegenerative diseases and cancer progression
价 格：￥电议型 号：T61906产 地：中国大陆
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T61904HSP90-IN-14；化合物 HSP90-IN-14HSP90-IN-14
HSP90-IN-14 (compound 4) is an effective Hsp90 inhibitor (Kd=0.26 μM). In MDCK cells, HSP90-IN-14 showed anti-influenza virus activity, the EC50 against influenza A/H3N2, A/H1N1 and B virus was 2.6, 3.9 and 17 μM, respectively.
价 格：￥电议型 号：T61904产 地：中国大陆
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T61899VEGFR2-IN-1；VEGFR2 抑制剂1VEGFR2-IN-1
VEGFR2-IN-1 is a selective and potent VEGFR2 inhibitor with antitumor activity that inhibits cell proliferation and migration and can be used in the study of breast cancer.
价 格：￥电议型 号：T61899产 地：中国大陆
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T61897SMO-IN-1；化合物 SMO-IN-1SMO-IN-1
SMO-IN-1 (Compound 15) is an oral effective Smoothened (SMO) inhibitor. The EC50 value of sonic Hh protein (shh) is 89 nM.
价 格：￥电议型 号：T61897产 地：中国大陆
