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  • T60686SARS-CoV-2 Mpro-IN-1；化合物 SARS-CoV-2 Mpro-IN-1SARS-CoV-2 Mpro-IN-1

    SARS-CoV-2 Mpro-IN-1 (compound 16b-3) is a potent, selective and irreversible SARS-CoV-2 main protease (Mpro) inhibitor (IC 50 = 116 nM) [1].

    价 格：￥电议型 号：T60686产 地：中国大陆

  • T60684FBA-IN-1；化合物 FBA-IN-1FBA-IN-1

    FBA-IN-1 (compound 2a11) is a first-in-class, covalent and allosteric inhibitor of fructose-1,6-bisphosphate aldolase(FBA) from Candida albicans(CaFBA). Furthermore, FBA-IN-1 can inhibit the Azole-resistant strains 103 growth with the MIC 80 of 1 μg/mL [1].

    价 格：￥电议型 号：T60684产 地：中国大陆

  • T60669Enpp-1-IN-10；化合物 Enpp-1-IN-10Enpp-1-IN-10

    Enpp-1-IN-10 (compound 1) is a potent inhibitor of Ecto-nucleotide pyrophosphatase/phosphodiesterases 1(ENPP1) with an Ki value of 3.866 μM that can be used in anticancer research [1].

    价 格：￥电议型 号：T60669产 地：中国大陆

  • T60660MAO-B-IN-14；化合物 MAO-B-IN-14MAO-B-IN-14

    MAO-B-IN-14 (Compound 9) is a potent and selective inhibitor of monoamine oxidase-B (MAO-B) with an IC 50 of 0.95 μM and a Ki of 0.55 μM for human MAO-B.

    价 格：￥电议型 号：T60660产 地：中国大陆

  • T60659Cdc7-IN-12；化合物 Cdc7-IN-12Cdc7-IN-12

    Cdc7-IN-12 (compound 1) is a potent inhibitor of CDC7 (IC 50 of <1 nM) that has the potential in the cancer research. Cdc7-IN-12 exhibits antiproliferative activities in COLO205 cells with IC 50 of 100-1000 nM [1].

    价 格：￥电议型 号：T60659产 地：中国大陆

  • T60654KDM4C-IN-1；KDM4C抑制剂1KDM4C-IN-1

    KDM4C-IN-1 is a selective and potent KDM4C inhibitor (IC50: 8 nM) with potential anticancer activity.KDM4C-IN-1 inhibits the growth of HepG2 and A549 cells, and can be used for the study of leukaemia.

    价 格：￥电议型 号：T60654产 地：中国大陆

  • T60651MAO-B-IN-16；化合物 MAO-B-IN-16MAO-B-IN-16

    MAO-B-IN-16 is a selective inhibitor of monoamine oxidase B (MAO-B ) (IC 50 = 1.55 μM) that can be used in the central nervous disorders study, for example, parkinson´s disease [1].

    价 格：￥电议型 号：T60651产 地：中国大陆

  • T60650MAO-B-IN-13；化合物 MAO-B-IN-13MAO-B-IN-13

    MAO-B-IN-13 (compound 12a) is a highly potent, reversible and blood-brain barrier (BBB) penetrant MAO-B inhibitor (IC50 = 10 nM). MAO-B-IN-13 shows neuroprotective and antioxidant activity which can be used in Parkinson’s disease research [1].

    价 格：￥电议型 号：T60650产 地：中国大陆

  • T60643FabH-IN-1；化合物 FabH-IN-1FabH-IN-1

    FabH-IN-1 (compound 3f) is effective against gram-positive and gram-negative as well as a good antioxidant. FabH-IN-1 is an inhibitor of bacterial 3-oxoacyl-[acyl-carrier-protein] synthase 3 (FabH) enzyme which is a broad-spectrum antimicrobial target [1].

    价 格：￥电议型 号：T60643产 地：中国大陆

  • T60630COX/5-LOX-IN-1；化合物 COX/5-LOX-IN-1COX/5-LOX-IN-1

    COX/5-LOX-IN-1 (compound 6b) is a potent COX/5-LOX dual inhibitor with the potential for inflammation diseases research. COX/5-LOX-IN-1 has IC50s of 1.07, 0.55, and 0.28 μM for COX-1, COX-2, and 5-LOX enzyme, respectively [1].

    价 格：￥电议型 号：T60630产 地：中国大陆

  • T60619CDK9-IN-15；化合物CDK9-IN-15CDK9-IN-15

    CDK9-IN-15 is a potent small molecule CDK9 inhibitor, which can block the phosphorylation of positive transcription elongation factor b (P-TEFb) on the C-terminal region of RNA Poly-II by degradation and inhibition of CDK9, inhibit transcription, and rapidly reduce the level of intracellular mRNA, thereby causing apoptosis of tumor cells.

    价 格：￥电议型 号：T60619产 地：中国大陆

  • T60614DHDPS-IN-1；化合物 DHDPS-IN-1DHDPS-IN-1

    DHDPS-IN-1 (compound 8) is a inhibitor of dihydrodipicolinate synthase(DHDPS) with IC50 of 39 μM that can be used in the area of antibacterial and herbicidal [1].

    价 格：￥电议型 号：T60614产 地：中国大陆

  • T60613Mab Aspartate Decarboxylase-IN-1；化合物 Mab?Aspartate Decarboxylase-IN-1Mab Aspartate Decarboxylase-IN-

    Mab Aspartate Decarboxylase-IN-1 is a potent inhibitor of aspartate decarboxylase (PanD) (IC50 = 56.3 μM) with antibacterial activity [1].

    价 格：￥电议型 号：T60613产 地：中国大陆

  • T60600Tubulin polymerization-IN-14；化合物 Tubulin polymerization-IN-14Tubulin polymerization-IN-14

    Tubulin polymerization-IN-14 (Compound 20a) is a tubulin polymerization inhibitor (IC 50 = 3.15 μM) that exhibits potent anti-vascular and anticancer activities including cancer cell apoptosis [1].

    价 格：￥电议型 号：T60600产 地：中国大陆

  • T60596TGFβ-IN-1；化合物 TGFβ-IN-1TGFβ-IN-1

    TGFβ-IN-1 is an antitumor growth and metastasis agent by inhibiting the transforming growth factor β signaling pathway.

    价 格：￥电议型 号：T60596产 地：中国大陆

  • T60595Quorum Sensing-IN-1；化合物 Quorum Sensing-IN-1Quorum Sensing-IN-1

    Quorum Sensing-IN-1 is a small-molecule inhibitor of quorum sensing.

    价 格：￥电议型 号：T60595产 地：中国大陆

  • T60589Cdc7-IN-17；化合物 Cdc7-IN-17Cdc7-IN-17

    Cdc7-IN-17 is a potent inhibitor of CDC7 with an IC 50 of <10 μM that can be used in cancer research [1].

    价 格：￥电议型 号：T60589产 地：中国大陆

  • T60583CDK1/2/4-IN-1；化合物 CDK1/2/4-IN-1CDK1/2/4-IN-1

    CDK1/2/4-IN-1 (compound 3a) is a potent inhibitor of CDK with IC 50 values of 1.47, 0.78 and 0.87 μM for CDK1, CDK2 and CDK4, respectively. CDK1/2/4-IN-1 can be used in cancer research. CDK1/2/4-IN-1 arrests cell cycle at G2/M phase and induces apoptosis. CDK1/2/4-IN-1 elevates the level of Bax, caspase-3, and P53 and decreases the level of Bcl-2 [1].

    价 格：￥电议型 号：T60583产 地：中国大陆

  • T60579CEase-IN-1；化合物 CEase-IN-1CEase-IN-1

    CEase-IN-1 (Compound A1H3) is a potent and selective inhibitor of cholesterol esterase (CEase) with an IC 50 of 0.36 μM. It can be used in hypercholesterolemia research [1].

    价 格：￥电议型 号：T60579产 地：中国大陆

  • T60573MAO-B-IN-15；化合物 MAO-B-IN-15MAO-B-IN-15

    MAO-B-IN-15 is a selective inhibitor of MAO-B that forms π-π interaction with Tyr 326 residue (IC 50 = 13.5 μM) which can be used in Parkinson’s disease research[1].

    价 格：￥电议型 号：T60573产 地：中国大陆

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