当前位置：易推广 > 上海陶术生物科技有限公司 > 产品展示
企业档案
会员类型：会员
已获得易推广信誉 等级评定
(0 -40)基础信誉积累，可浏览访问
(41-90)良好信誉积累，可接洽商谈
(91+ )优质信誉积累，可持续信赖
易推广会员：5年
工商认证 【已认证】
最后认证时间：
注册号： 【已认证】
法人代表： 【已认证】
企业类型：生产商 【已认证】
注册资金：人民币万 【已认证】
产品数：86101
参观次数：3858640
自主品牌
已选条件
-
T61206AChE/BChE/BACE-1-IN-1；化合物 AChE/BChE/BACE-1-IN-1AChE/BChE/BACE-1-IN-1
AChE/BChE/BACE-1-IN-1 (Compound 4k) is an orally active inhibitor that targets acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and β-site amyloid precursor protein cleaving enzyme 1 (BACE-1). It displays IC50 values of 0.058 μM, 0.082 μM, and 0.115 μM against hAChE, hBChE, and hBACE-1, respectively. AChE/BChE/BACE-1-IN-1 exhibits significant binding affinity with PAS-AChE, excellent ability to cross the blood-brain barrier, potential disassembly of amyloid-beta (Aβ) aggregates, and ne
价 格：￥电议型 号：T61206产 地：中国大陆
-
T61202TDO-IN-1；TDO抑制剂1TDO-IN-1
TDO-IN-1 is an orally active, potent, and selective inhibitor of tryptophan 2,3-dioxygenase (TDO), which inhibits indoleamine-2,3-dioxygenase.TDO-IN-1 has antitumor activity and is able to act by reversing local immune tolerance in tumor tissues.
价 格：￥电议型 号：T61202产 地：中国大陆
-
T61198FAAH/MAGL-IN-1；化合物 FAAH/MAGL-IN-1FAAH/MAGL-IN-1
FAAH/MAGL-IN-1, also known as compound SIH 3, is a highly effective inhibitor of FAAH (fatty acid amide hydrolase) and MAGL (monoacylglycerol lipase). It exhibits IC50 values of 31 nM and 29 nM against FAAH and MAGL, respectively. This compound shows promising potential for advancing research in the field of neuropathic pain [1].
价 格：￥电议型 号：T61198产 地：中国大陆
-
T61196COX-1/2-IN-1；化合物 COX-1/2-IN-1COX-1/2-IN-1
COX-1/2-IN-2, a potent inhibitor of both COX-1 and COX-2, demonstrates significant inhibitory activity, with IC50 values of 13.9 ± 3.21 μM for COX-1 and 6.4 ± 0.74 μM for COX-2, respectively [1].
价 格：￥电议型 号：T61196产 地：中国大陆
-
T61169PqsR-IN-1；化合物 PqsR-IN-1PqsR-IN-1
PqsR-IN-1 (Compound 18) is a potent inhibitor of PqsR, which is a transcriptional regulator involved in the quorum sensing mechanism of Pseudomonas aeruginosa. This compound effectively reduces the production of pyocyanin and exhibits minimal cytotoxicity [1].
价 格：￥电议型 号：T61169产 地：中国大陆
-
T61167PptT-IN-1；化合物 PptT-IN-1PptT-IN-1
PptT-IN-1 (compound 5j) is a highly potent inhibitor (IC50: 2.8 μM) of phosphopantetheinyl phosphoryl transferase (PptT), a crucial enzyme involved in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. This compound shows considerable potential for tuberculosis research [1].
价 格：￥电议型 号：T61167产 地：中国大陆
-
T61166α-Glucosidase-IN-16；化合物 α-Glucosidase-IN-16α-Glucosidase-IN-16
α-Glucosidase-IN-16 is a highly effective and orally bioavailable inhibitor of α-glucosidase, displaying a remarkable IC50 value of 3.28 μM. This compound demonstrates the ability to significantly decrease blood glucose levels in diabetic rats induced by Streptozotocin. Notably, α-Glucosidase-IN-16 also exhibits noteworthy antidiabetic activity [1].
价 格：￥电议型 号：T61166产 地：中国大陆
-
T61137VEGFR-2-IN-19；化合物 VEGFR-2-IN-19VEGFR-2-IN-19
VEGFR-2-IN-19 (Compound 15b) is a highly efficacious inhibitor of VEGFR2, a receptor involved in angiogenesis. Its mechanism of action involves the induction of cellular apoptosis and elevation of intracellular reactive oxygen species. Due to these properties, VEGFR-2-IN-19 holds promise as an effective anticancer agent [1].
价 格：￥电议型 号：T61137产 地：中国大陆
-
T61136Enpp-1-IN-11；化合物 Enpp-1-IN-11Enpp-1-IN-11
Enpp-1-IN-11 (compound 23) is a highly potent inhibitor of Ecto-nucleotide pyrophosphatase/phosphodiesterases 1 (ENPP1), with a Ki value of 45 nM. It demonstrates excellent stability in human and mouse plasma and exhibits low clearance in both human and mouse liver microsomes. Enpp-1-IN-11 holds promise for anticancer research [1].
价 格：￥电议型 号：T61136产 地：中国大陆
-
T61135β-N-Acetyl-D-hexosaminidase-IN-1；化合物 β-N-Acetyl-D-hexosaminidase-IN-1β-N-Acetyl-D-hexosaminidase-IN-
β-N-Acetyl-D-hexosaminidase-IN-1 is a newly discovered chemical compound that acts as an inhibitor for β-N-acetyl-D-hexosaminidase. It exhibits a Ki value of 3.72 μM, indicating its potency in inhibiting the enzyme´s activity.
价 格：￥电议型 号：T61135产 地：中国大陆
-
T61132NLRP3-IN-11；NLRP3抑制剂11NLRP3-IN-11
NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.
价 格：￥电议型 号：T61132产 地：中国大陆
-
T61131MAO-B-IN-11；化合物 MAO-B-IN-11MAO-B-IN-11
MAO-B-IN-11, also known as Compound 8c, is a highly potent inhibitor of monoamine oxidase B (MAO-B), with an IC50 value of 1.3 μM. Additionally, MAO-B-IN-11 exhibits neuroprotective properties [1].
价 格：￥电议型 号：T61131产 地：中国大陆
-
T61121NusB-IN-1；化合物 NusB-IN-1NusB-IN-1
NusB-IN-1 (Compound 22r) is a highly effective bacterial rRNA synthesis inhibitor, administered orally. It exhibits potent antimicrobial activity against MRSA and VRSA [1].
价 格：￥电议型 号：T61121产 地：中国大陆
-
T61119MtDTBS-IN-1；化合物 MtDTBS-IN-1MtDTBS-IN-1
MtDTBS-IN-1 is a notably potent binder (K_D = 57 nM) and inhibitor (K_i = 5 μM) of MtDTBS.
价 格：￥电议型 号：T61119产 地：中国大陆
-
T61118CD73-IN-12；化合物 CD73-IN-12CD73-IN-12
CD73-IN-12 is a highly effective CD73 inhibitor that displays strong potential in tumor suppression. CD73, an enzyme intricately linked to tumor development, angiogenesis, and metastasis, is significantly inhibited by CD73-IN-12. This compound holds promise in the formulation of therapeutic medications targeting tumor-related diseases[1].
价 格：￥电议型 号：T61118产 地：中国大陆
-
T61106GRP78-IN-1；化合物 GRP78-IN-1GRP78-IN-1
GRP78-IN-1 displays interactions with specific residues on the GRP78 protein with a binding energy of -8.07 kcal/mol. This compound possesses potent cytotoxic and anti-proliferative effects on cancer cells, particularly demonstrating promising apoptosis in breast cancer cells and wound healing properties [1].
价 格：￥电议型 号：T61106产 地：中国大陆
-
T61101FLT3-IN-13；化合物 FLT3-IN-13FLT3-IN-13
FLT3-IN-13 (compound 20) is a highly effective inhibitor targeting both topoisomerase II and FLT3 proteins in leukemic cells. It exhibits potent activity against these targets, with IC50 values of 2.26 μM for both. Moreover, FLT3-IN-13 induces cell cycle arrest at the G2/M phase and promotes apoptosis. Notably, it displays considerable anticytotoxic activity, specifically against leukemia [1].
价 格：￥电议型 号：T61101产 地：中国大陆
-
T61098RUNX1/ETO tetramerization-IN-1；化合物 RUNX1/ETO tetramerization-IN-1RUNX1/ETO tetramerization-IN-1
RUNX1/ETO tetramerization-IN-1 is a small-molecule inhibitor that specifically targets NHR2 of RUNX1/ETO, effectively inhibiting the tetramerization process. With an EC50 value of 0.25 μM, this compound successfully restores gene expression that has been down-regulated by RUNX1/ETO. Furthermore, RUNX1/ETO tetramerization-IN-1 demonstrates promising anti-leukemic activity by inhibiting the proliferation of SKNO-1 cells dependent on RUNX1/ETO and significantly reducing RUNX1/ETO-associated tumor g
价 格：￥电议型 号：T61098产 地：中国大陆
-
T61069Tubulin polymerization-IN-15；化合物 Tubulin polymerization-IN-15Tubulin polymerization-IN-15
Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].
价 格：￥电议型 号：T61069产 地：中国大陆
-
T61067MurB-IN-1；化合物 MurB-IN-1MurB-IN-1
MurB-IN-1 (compound 44) is a potent inhibitor of MurB, an essential enzyme involved in the synthesis of bacterial cell wall. With a binding affinity of K d 3.57 μM, MurB-IN-1 effectively hinders the activity of MurB, presenting a promising therapeutic option against P. aeruginosa, a highly virulent and opportunistic pathogen associated with severe infections and mortality [1].
价 格：￥电议型 号：T61067产 地：中国大陆
