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  • T61053CD73-IN-11；化合物 CD73-IN-11CD73-IN-11

    CD73-IN-11 is able to used for tumor-related diseases medicament preparing. CD73-IN-11 is an effective CD73 inhibitor. CD73 can catalyze the production of adenosine from extracellular 5´-phosphate adenosine (5´-AMP) which induce immunosuppression and promote tumor proliferation and/or metastasis [1].

    价 格：￥电议型 号：T61053产 地：中国大陆

  • T61051ANO1-IN-1；化合物ANO1-IN-1ANO1-IN-1

    ANO1-IN-1, a selective ANO1 channel blocker, inhibited ANO1 and ANO2 with IC50 values of 2.56 μM and 15.43 μM, respectively.ANO1-IN-1 had a significant inhibitory effect on the proliferation of glioma cells.

    价 格：￥电议型 号：T61051产 地：中国大陆

  • T61049AChE-IN-11；化合物 AChE-IN-11AChE-IN-11

    AChE-IN-11 (compound 5C) can be used in the Alzheimer´s disease research with neuroprotective effects and good antioxidant activity (ORAC = 2.5 eq). AChE-IN-11 is a good multifunctional agent with IC 50 values of 7.9 μM, 9.9 μM, and 8.3 μM against AChE, MAO-B, and BACE1. AChE-IN-11 has a mixed-type AChE inhibition that can bind to the CAS and PAS of AChE. AChE-IN-11 is also a selective metal ions chelator [1].

    价 格：￥电议型 号：T61049产 地：中国大陆

  • T61044HDAC6-IN-11；化合物 HDAC6-IN-11HDAC6-IN-11

    HDAC6-IN-11 (Compound 9) has anti-proliferative activities against cancer cells. HDAC6-IN-11 is a selective inhibitor of HDAC6 with the IC50 value of 20.7 nM. The selectivity of HDAC6-IN-11 is more than 300-fold over HDAC other isoforms [1].

    价 格：￥电议型 号：T61044产 地：中国大陆

  • T61038VEGFR-2-IN-10；化合物 VEGFR-2-IN-10VEGFR-2-IN-10

    VEGFR-2-IN-10 has enhanced antiangiogenic potency against VEGFR2 phosphorylation induced by VEGF with an IC50 value of 0.7 μM and no cytotoxic effects.

    价 格：￥电议型 号：T61038产 地：中国大陆

  • T61037Glycosyltransferase-IN-1；Glycosyltransferase 抑制剂1Glycosyltransferase-IN-1

    Glycosyltransferase-IN-1 is a glycosyltransferase inhibitor with bacteriostatic activity, inhibiting MSSA, MRSA, Bacillus subtilis, and Enterobacteriaceae.

    价 格：￥电议型 号：T61037产 地：中国大陆

  • T6103417β-HSD1-IN-1；化合物 17β-HSD1-IN-117β-HSD1-IN-1

    17β-HSD1-IN-1 (Compound 1) can be used in the non-small cell lung cancer (NSCLC) research. 17β-HSD1-IN-1 is a highly selective inhibitor of 17β-HSD1 with IC50 values of 5.6 and 3155 nM for 17β-HSD1 and 17β-HSD2, respectively [1].

    价 格：￥电议型 号：T61034产 地：中国大陆

  • T61030STAT3-IN-11；STAT3 抑制剂 11STAT3-IN-11

    STAT3-IN-11 is a selective STAT3 inhibitor with inhibitory effects on phosphorylation of the STAT3pTyr705 site and phosphorylation of Survivin.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound for the treatment of cancer.

    价 格：￥电议型 号：T61030产 地：中国大陆

  • T61022LSD1-IN-17；化合物 LSD1-IN-17LSD1-IN-17

    LSD1-IN-17 (compound 5b) is a potent inhibitor of LSD1 that inhibits LSD1-CoREST, MAO-A and MAO-B, with IC 50 values of 0.005, 0.028, and 0.820 μM, respectively. LSD1-IN-17 exhibits cell growth arrest in prostate cancer LNCaP cells with an IC50 value of 17.2 μM [1].

    价 格：￥电议型 号：T61022产 地：中国大陆

  • T61021LSD1-IN-16；化合物 LSD1-IN-16LSD1-IN-16

    LSD1-IN-16 (compound 4b) is a potent inhibitor of LSD1 that inhibits LSD1-CoREST, MAO-A and MAO-B with IC50 values of 0.015, 0.024, and 0.366 μM, respectively. LSD1-IN-16 exhibits cell growth arrest in prostate cancer LNCaP cells with an IC50 value of 15.2 μM [1].

    价 格：￥电议型 号：T61021产 地：中国大陆

  • T61014Galectin-8-IN-1；化合物 Galectin-8-IN-1Galectin-8-IN-1

    Galectin-8-IN-1 is a selective ligand for the galectin-8 N-terminal domain (galectin-8N) with a Kd value of 48 μM. Galectin-8-IN-1 is 15-fold more selective than galectin-3 and even better than other mammalian galectins.

    价 格：￥电议型 号：T61014产 地：中国大陆

  • T61009Complex III-IN-1；化合物 Complex III-IN-1Complex III-IN-1

    Complex III-IN-1 (Compd 4c-2) is an inhibitor of complex III with antifungal activity. The EC50 value of Complex III-IN-1 against sclerotinia sclerotiorum is 18.53 mg/L [1].

    价 格：￥电议型 号：T61009产 地：中国大陆

  • T61004AEP-IN-1；化合物 AEP-IN-1AEP-IN-1

    APE-IN-1 can be used for the early diagnosis and drug research of Alzheimer´s disease. APE-IN-1 is a potent Asparagine endopeptidase (AEP) inhibitor with IC 50 value of 89 nM [1].

    价 格：￥电议型 号：T61004产 地：中国大陆

  • T61000CD73-IN-10；化合物 CD73-IN-10CD73-IN-10

    CD73-IN-10 can be used in preparing tumor-related diseases medicament. CD73-IN-10 is a potent CD73 inhibitor that can catalyze the adenosine production from extracellular 5´-phosphate adenosine (5´-AMP). Adenosine induces immunosuppression and can promote tumor proliferation and/or metastasis [1].

    价 格：￥电议型 号：T61000产 地：中国大陆

  • T60991Factor VII-IN-1；化合物 Factor VII-IN-1Factor VII-IN-1

    Factor VII-IN-1 (example 43) has anticoagulant activities that is a potent factor VII (FVII) inhibitor with an IC50 value of 1.1 μM [1].

    价 格：￥电议型 号：T60991产 地：中国大陆

  • T60983BChE-IN-14；化合物 BChE-IN-14BChE-IN-14

    BChE-IN-14 (compound 19c) can restore cognitive impairment in vivo that can be used in the Alzheimer’s disease research. BChE-IN-14 has primary cell safety and good blood brain barrier permeability. BChE-IN-14 is a selective inhibitor of butyrylcholinesterase (BChE) with IC50 values of 0.011 μM and 0.23 μM for hBChE and eqBChE, respectively [1].

    价 格：￥电议型 号：T60983产 地：中国大陆

  • T60982PI5P4Ks-IN-1；化合物 PI5P4Ks-IN-1PI5P4Ks-IN-1

    PI5P4Ks-IN-1 (compound 7) is an active compound which engages PI5P4Kγ[1].

    价 格：￥电议型 号：T60982产 地：中国大陆

  • T60981TRPC4/5-IN-1；化合物 TRPC4/5-IN-1TRPC4/5-IN-1

    TRPC4/5-IN-1 can be used for the research of skin inflammatory diseases and proteinuric kidney diseases. TRPC4/5-IN-1 is a potent inhibitor of TRP channel 5/4 (TRPC5/4) with IC50 values of 0.54 μM and 2.06 μM, respectively. [1].

    价 格：￥电议型 号：T60981产 地：中国大陆

  • T60980PIKfyve-IN-1；化合物 PIKfyve-IN-1PIKfyve-IN-1

    PIKfyve-IN-1 is a cell-active and highly potent chemical probe that can be used for the PIKfyve research in virology. PIKfyve-IN-1 inhibits phosphatidylinositol-3phosphate 5-kinase (PIKfyve) (IC 50 = 6.9 nM)[1].

    价 格：￥电议型 号：T60980产 地：中国大陆

  • T60974MetRS-IN-1；化合物 MetRS-IN-1MetRS-IN-1

    MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].

    价 格：￥电议型 号：T60974产 地：中国大陆

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