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T71091Y2-Antagonist-2；化合物 Y2-Antagonist-2Y2-Antagonist-2
Y2-Antagonist-2 is a novel, selective, soluble non-?peptidic NPY Y2 receptor antagonist with enhanced CNS exposure.
价 格：￥电议型 号：T71091产 地：中国大陆
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T70181FFA3-Antagonist-6；化合物 FFA3-Antagonist-6FFA3-Antagonist-6
FFA3-Antagonist-6 is a PAM-antagonist of the function of C3 at FFA3.
价 格：￥电议型 号：T70181产 地：中国大陆
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T67946EP2 receptor antagonist-2；EP2受体拮抗剂2EP2 receptor antagonist-2
EP2 receptor antagonist-2 (CID891729) is a compound that not only serves as an antagonist to the EP2 receptor, blocking its activation by PGE2, but also reduces lactate dehydrogenase (LDH) release triggered by N-methyl-D-aspartate (NMDA).
价 格：￥电议型 号：T67946产 地：中国大陆
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T67915Succinate/succinate receptor antagonist 1；琥珀酸/琥珀酸受体拮抗剂1Succinate/succinate receptor antagonist 1
Succinate/succinate receptor antagonist 1 is a potent succinate receptor antagonist. Succinate/succinate receptor antagonist 1 interrupts succinate signals in gingival tissue and inhibits the activation of SucnRl Antagonist 1. Its IC50 value is 20 μsouth of the coast. Succinate/succinate receptor antagonist 1 can be used to treat periodontal disease.
价 格：￥电议型 号：T67915产 地：中国大陆
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T64302XIAP/cIAP1 antagonist-1；化合物 XIAP/cIAP1 antagonist-1XIAP/cIAP1 antagonist-1
XIAP/cIAP1 antagonist-1 is a potent, orally active XIAP/cIAP1 antagonist that acts on XIAP (EC50: 5.1 nM) and cIAP1 (EC50: 0.32 nM). xIAP/cIAP1 antagonist-1 dose-dependently inhibits tumour growth in vivo.
价 格：￥电议型 号：T64302产 地：中国大陆
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T64285Protease-Activated Receptor-1 antagonist 2；化合物 Protease-Activated Receptor-1 antagonist?2Protease-Ac
Protease-Activated Receptor-1 antagonist 2 is a selective, orally active protease-activated receptor-1 (PAR-1) antagonist (IC50: 7 nM). It has shown good pharmacokinetic properties and can be used for studies related to cardiovascular disease (CVD) such as atherosclerosis and restenosis.
价 格：￥电议型 号：T64285产 地：中国大陆
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T64242CCR1 antagonist 11 hydrochloride；化合物 CCR1 antagonist 11 hydrochlorideCCR1 antagonist 11 hydrochlorid
CCR1 antagonist 11 hydrochloride (A1B1) is an orally active CCR1 antagonist that acts on hCCR1 (IC50: 0/.03 μM), mCCR1 (IC50: 0.58 μM), rCCR1 (IC50: 0.32 μM). 11 hydrochloride can be used to study rheumatoid arthritis and other related inflammatory diseases.
价 格：￥电议型 号：T64242产 地：中国大陆
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T64174Vasopressin V2 receptor antagonist 1；化合物 Vasopressin V2 receptor antagonist 1Vasopressin V2 receptor
Vasopressin V2 receptor antagonist 1 (Compound 4g) is a vasopressin V2receptor (V2R) antagonist (Ki: 3.8 nM). dominant polycystic kidney disease (ADPKD).
价 格：￥电议型 号：T64174产 地：中国大陆
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T64171LXR antagonist 2；化合物 LXR antagonist 2LXR antagonist 2
LXR antagonist 2 (compound 10rr) is a potent LXR (liver X receptor) inverse agonist, acting on LXRβ (IC50: 0.36 μM) and LXRα (IC50: 2.25 μM). LXR antagonist 2 is an adipogenesis inhibitor that downregulates LXR target genes SREBP-1c, ACC, FAS and SCD-1. LXR antagonist 2 exhibits hypolipidemic activity in Triton WR-1339-induced hyperlipidemic mice.
价 格：￥电议型 号：T64171产 地：中国大陆
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T64144FXR antagonist 1；化合物 FXR antagonist 1FXR antagonist 1
FXR antagonist 1 is a selective, orally active intestinal FXR antagonist with an IC50 value of 2.1 μM. FXR antagonist 1 antagonises intestinal FXR and selectively inhibits intestinal FXR signalling by feedback activation of hepatic FXR. FXR antagonist 1 can improve liver steatosis, inflammation and fibrosis in the NASH (non-alcoholic steatohepatitis) model and can be used to study NASH.
价 格：￥电议型 号：T64144产 地：中国大陆
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T64122AT1R antagonist 2；化合物 AT1R antagonist 2AT1R antagonist 2
AT1R antagonist 2 is a potent AT1R selective ligand with good AT1R affinity (Ki: 26 nM).
价 格：￥电议型 号：T64122产 地：中国大陆
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T64119SSTR5 antagonist 2 hydrochloride；化合物 SSTR5 antagonist 2 hydrochlorideSSTR5 antagonist 2 hydrochlorid
SSTR5 antagonist 2 hydrochloride is a potent, orally active, selective growth hormone inhibitory hormone (receptor) subtype 5 (SSTR5) antagonist that has shown potential for investigation in type 2 diabetes.
价 格：￥电议型 号：T64119产 地：中国大陆
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T64026ERα antagonist 1；化合物 ERα antagonist 1ERα antagonist 1
ERα antagonist 1 is a selective, potent, covalent estrogen receptor alpha (ERα) antagonist that blocks the cell cycle of MCF-7 cells in G0/G1 phase and induces apoptosis.
价 格：￥电议型 号：T64026产 地：中国大陆
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T64024Dopamine D3 receptor antagonist-1；化合物 Dopamine D3 receptor antagonist-1Dopamine D3 receptor antagoni
Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor selective or multi-targeting ligand with a Ki value of 1.58 nM that has demonstrated therapeutic potential for central nervous system disorders.
价 格：￥电议型 号：T64024产 地：中国大陆
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T63960A3AR antagonist 1；化合物 A3AR antagonist 1A3AR antagonist 1
A3AR antagonist 1 is a potent and selective human A3adenosine receptor (AR) antagonist (Ki: 4.63) and has no affinity for the rat A3AR.
价 格：￥电议型 号：T63960产 地：中国大陆
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T63952GRPR antagonist-2；化合物 GRPR antagonist-2GRPR antagonist-2
GRPR antagonist-2 is a potent antagonist of the gastrin-releasing peptide receptor (GRPR) and exhibits anticancer effects by being cytotoxic to certain cancer cells (able to act on HGC-27 cells (IC50: 0.77 μM) and Pan02 cells (IC50: 2.5 μM)).
价 格：￥电议型 号：T63952产 地：中国大陆
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T63947GRPR antagonist-1；化合物 GRPR antagonist-1GRPR antagonist-1
GRPR antagonist-1 is a potent antagonist of the gastrin-releasing peptide receptor (GRPR) and is cytotoxic to certain cancer cells (able to act on PC3 cells (IC50: 4.97 μM), Pan02 cells (IC50: 4.36 μM), HGC-27 cells (IC50: 3.40 μM)). antagonist-1 was able to reduce the level of Bcl-2 and increase the level of Bax, thereby inhibiting the viability of HGC-27 cells and causing apoptosis, and exhibited anti-cancer effects.
价 格：￥电议型 号：T63947产 地：中国大陆
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T63914Estrogen receptor antagonist 3；化合物 Estrogen receptor antagonist 3Estrogen receptor antagonist 3
Estrogen receptor antagonist 3 is a potent degradation agent of the estrogen receptor (ER). Estrogen signalling systems play an important role in the regulation of cell growth, differentiation and apoptosis, and Estrogen receptor antagonist 4 has shown potential for research into cancer diseases.
价 格：￥电议型 号：T63914产 地：中国大陆
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T63812MrgprX2 antagonist-8；MrgprX2拮抗剂8MrgprX2 antagonist-8
MrgprX2 antagonist-8 is an MrgprX2 antagonist that can be used to study inflammatory diseases.
价 格：￥电议型 号：T63812产 地：中国大陆
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T63766MrgprX2 antagonist-7；化合物 MrgprX2 antagonist-7MrgprX2 antagonist-7
MrgprX2 antagonist-7 is an anti-allergic agent with significant anti-allergic effects and inhibits mast cell degranulation.
价 格：￥电议型 号：T63766产 地：中国大陆
