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T79097PROTAC IRAK4 degrader-8；化合物 PROTAC IRAK4 degrader-8PROTAC IRAK4 degrader-8
PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 of 15.5 nM [1].
价 格：￥电议型 号：T79097产 地：中国大陆
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T79067PROTAC BTK Degrader-3；化合物 PROTAC BTK Degrader-3PROTAC BTK Degrader-3
PROTAC BTK Degrader-3 is a potent degrader of Bruton´s tyrosine kinase (BTK), exhibiting a DC50 (median degradation concentration) of 10.9 nM in Mino cells. This compound shows promise for research into B-cell malignancies, such as chronic lymphoid malignancies [1].
价 格：￥电议型 号：T79067产 地：中国大陆
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T78983STAT3 degrader-2；化合物 STAT3 degrader-2STAT3 degrader-2
STAT3 Degrader-2 is a PROTAC-based compound that effectively reduces the total STAT3 protein levels, and is utilized in the research of cancer and various diseases [1].
价 格：￥电议型 号：T78983产 地：中国大陆
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T78956PROTAC BRD3/BRD4-L degrader-2；化合物 PROTAC BRD3/BRD4-L degrader-2PROTAC BRD3/BRD4-L degrader-2
PROTAC BRD3/BRD4-L degrader-2, a PROTAC molecule, selectively degrades cellular BRD3 and BRD4-L with K i values of 16.91 and 2.8 nM, respectively, and exhibits robust antitumor activity in mouse xenograft models, serving as a research tool for cancer [1].
价 格：￥电议型 号：T78956产 地：中国大陆
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T78928PROTAC CDK9 degrader-8；化合物 PROTAC CDK9 degrader-8PROTAC CDK9 degrader-8
PROTAC CDK9 Degrader-8 (Compound 21) is a potent degrader of CDK9 with an IC50 of 0.01 μM, utilized in cancer research [1].
价 格：￥电议型 号：T78928产 地：中国大陆
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T78811PROTAC AR-NTD degrader 1；化合物 PROTAC AR-NTD degrader 1PROTAC AR-NTD degrader 1
PROTAC AR-NTD antagonist 1 (compound 18) is a small molecule belonging to the protein-targeting chimeras (PROTACs) that selectively targets the N-terminal domain (AR-NTD) of the Androgen Receptor variant AR-V7. By antagonizing AR-NTD, this compound effectively degrades AR-V7 protein and triggers apoptosis in prostate cancer (PC) cells, with degradation efficiencies in VCaP cells recorded at 62.2% (1 μM) and 71.1% (5 μM), as noted in reference [1].
价 格：￥电议型 号：T78811产 地：中国大陆
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T78782PROTAC BTK Degrader-6；化合物 PROTAC BTK Degrader-6PROTAC BTK Degrader-6
PROTAC BTK Degrader-6 (Compound 15), with a DC50 of 3.18 nM, exhibits anti-inflammatory properties by inhibiting NF-κB activation and suppressing the expression of pro-inflammatory cytokines, such as IL-1β and IL-6 [1].
价 格：￥电议型 号：T78782产 地：中国大陆
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T78676ERα degrader 6；化合物 ERα degrader 6ERα degrader 6
ERα degrader 6 (Compound 31q) is an ERα degrader with a K I of 75 nM and also inhibits ARO with an IC50 value of 37.7 nM. It effectively inhibits tumor growth in the MCF-7 tumor xenograft model and has applications in breast cancer research [1].
价 格：￥电议型 号：T78676产 地：中国大陆
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T78647PROTAC BRD4 Degrader-16；化合物 PROTAC BRD4 Degrader-16PROTAC BRD4 Degrader-16
PROTAC BRD4 Degrader-16 is a potent degrader of BRD4, exhibiting IC50 values of 34.58 nM for BRD4 (BD1) and 40.23 nM for BRD4 (BD2). It significantly reduces Cyclin B1 expression, thereby impeding G2/M phase progression, and induces apoptosis in MV-4-11 cells [1].
价 格：￥电议型 号：T78647产 地：中国大陆
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T78629PROTAC α-synuclein degrader 3；化合物 PROTAC α-synuclein degrader 3PROTAC α-synuclein degrader 3
PROTAC α-synuclein degrader 3 (compound 5) serves as a potent and selective agent for degrading α-synuclein and is utilized in Parkinson´s disease research [1].
价 格：￥电议型 号：T78629产 地：中国大陆
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T77976PROTAC Her3 Degrader-8；化合物 PROTAC Her3 Degrader-8PROTAC Her3 Degrader-8
PROTAC Her3 Degrader-8 (Compound PP2) is a proteolysis targeting chimera (PROTAC) capable of degrading the Her3 protein in vitro and within cellular assays, with potential to investigate diseases modulated by HER family proteins [1].
价 格：￥电议型 号：T77976产 地：中国大陆
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T77975PROTAC BRD9 Degrader-6；化合物 PROTAC BRD9 Degrader-6PROTAC BRD9 Degrader-6
PROTAC BRD9 Degrader-6, with an IC50 value of 0.13 nM, is a potent degrader of BRD9 suitable for research on BAF complex-related disorders [1].
价 格：￥电议型 号：T77975产 地：中国大陆
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T77974PROTAC BCR-ABL Degrader-1；化合物 PROTAC BCR-ABL Degrader-1PROTAC BCR-ABL Degrader-1
PROTAC BCR-ABL Degrader-1 (compound PROTAC 1), featuring a 2-oxoethyl linker, promotes Bcr-Abl degradation through the ubiquitin-proteasome pathway and demonstrates antiproliferative effects on K562 cells, suggesting its utility in cancer research [1].
价 格：￥电议型 号：T77974产 地：中国大陆
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T77936PROTAC BRD9 Degrader-4；化合物 PROTAC BRD9 Degrader-4PROTAC BRD9 Degrader-4
PROTAC BRD9 Degrader-4 is a bifunctional degrader targeting BRD9, designed for cancer research applications.
价 格：￥电议型 号：T77936产 地：中国大陆
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T77926PROTAC KRAS G12C degrader-1；化合物 PROTAC KRAS G12C degrader-1PROTAC KRAS G12C degrader-1
PROTAC KRAS G12C degrader-1, a cereblon-based degrader, promotes CRBN/KRAS G12C dimerization and facilitates the degradation of GFP-KRAS G12C in reporter cells [1].
价 格：￥电议型 号：T77926产 地：中国大陆
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T77922HDAC6 degrader-1；化合物 HDAC6 degrader-1HDAC6 degrader-1
HDAC6 degrader-1, a proteolysis-targeting chimeric molecule (PROTAC), incorporates the selective HDAC6 inhibitor Nexturastat A (Nex A) for HDAC6 binding, a linker, and an E3 ligase recruiting ligand. This compound effectively induces HDAC6 degradation, displays superior selectivity over other HDAC isoforms, and efficiently inhibits cell proliferation [1].
价 格：￥电议型 号：T77922产 地：中国大陆
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T75149PROTAC BRD4 Degrader-19；化合物 PROTAC BRD4 Degrader-19PROTAC BRD4 Degrader-19
PROTAC BRD4 Degrader-19 (compound 176) is a proteolysis-targeting chimera (PROTAC) designed to specifically degrade the BRD4 protein, offering potential utility in cancer research [1].
价 格：￥电议型 号：T75149产 地：中国大陆
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T75136IRAK degrader-1；化合物 IRAK degrader-1IRAK degrader-1
IRAK degrader-1 (example I-3) is a potent IRAK degrader [1] .
价 格：￥电议型 号：T75136产 地：中国大陆
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T75125ITK degrader 2；化合物 ITK degrader 2ITK degrader 2
ITK Degrader 2 (Compound 30) functions as a modulator for targeted ubiquitination and serves as a molecule for targeted protein degradation, specifically degrading ITK [1].
价 格：￥电议型 号：T75125产 地：中国大陆
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T75099PROTAC STAT3 degrader-2；化合物 PROTAC STAT3 degrader-2PROTAC STAT3 degrader-2
PROTAC STAT3 degrader-2 is a selective and efficacious PROTAC degrader of STAT3 protein with a DC 50 of 3.54 μM in Molm-16 Cell. PROTAC STAT3 degrader-2 has the potential for cancer research [1] .
价 格：￥电议型 号：T75099产 地：中国大陆
